Rush - Advanced Pharmacology - NSG 531 - Exam 4 Questions and Correct Answers the Latest Update

Ginseng taken for: Nervousness, Agitation, Insomnia, Diarrhea, Headaches, Heart Palpitation Do not take with MAO inhibitors. Can alter affects with heart medications. Can increase the risk of bleeding when taken with blood clotting drugs CI: Neuro, Heart, MAO, bleeding, coag drugs Ma Huang (Ephedra) Dangerously elevate blood pressure, stimulate heart rate, and CNS Associated with stroke, MI, and death Banned > 10 mg in U.S. with exception of traditional Asian medicine Metabolife Used for weight loss, allergies, asthma, bronchitis, fever, headache arginine Arginine is used for treatment of heart and blood vessel conditions including congestive heart failure (CHF), chest pain, high blood pressure, and coronary artery disease. Don't use if: excess body acid high levels of potassium in the blood #Examify | #OnlineExams | #TestPrep | #StudyResources | #AcademicSuccess | #ExamPreparation | #QuizTime | #LearningTools | #Education | #StudentSupport Examify | Smart Grades | Latest update sickle cell anemia heart attack within the last 30 days renal tubular acidosis decreased kidney function Don't use with nitro pt. education for herbs and nutrients 1. herbs and nutrients have bioactive properties and have the same safety issues as drugs 2. always consult a reliable source before adding 3. consider when researching what are the credentials of the author of the website, what evidence is there to support their claims, are there any financial interests to influence the claims of the auther biological basis of drug/herb/nutrient interactions absorption (changing pH or motility of the GI tract) Distribution (displacing agents that are bound to plasma proteins Biotransformation (inducing or inhibiting CYP450 enzymes) receptor binding (competitive and noncompetitive antagonism Gompertzian Kinetics Cancer cells lack of normal regulating factors leading to abnormal growth You can go from 0 to 10^9 before symptoms This bounces because you go on and off of chemo #Examify | #OnlineExams | #TestPrep | #StudyResources | #AcademicSuccess | #ExamPreparation | #QuizTime | #LearningTools | #Education | #StudentSupport Examify | Smart Grades | Latest update That's why we do multiple rounds - so you initiate the next round of chemo before you get back to where we started If you initiate chemo at a lower tumor mass you will get a better response in a shorter amount of time Mechanisms of drug resistance reduced intracellular drug concentration through drug inactivation mechanisms, reduced uptake, drug efflux pumps change in target due to mutation in drug target insensitivity to apoptosis due to mutation in p53 chemotherapeutics: antemetabolites inhibit DNA synthesis enzymes works in the s phase 5FU binds to tymidylase synthase catalizes the reaction of converting dUMP to dTMP if you interrupt this you interrupt synthesis of DNA chemotherapeutics: alkylating agents Bind to DNA binds to DNA at the alky