©NINJANERD 2024/2025. YEAR PUBLISHED 2024.
PHAR 100 Exam Questions and Answers
100% Solved | Graded A+
What 3 civilizations were mentioned in the module about the history of
drugs and what drug was associated with them? - ✔✔Ancient Greece
(opium and codeine), Ancient China (ma Huang), and Ancient Egypt
(purgatives)
What poisons were mentioned in the module? - ✔✔Curare and Ergot
What is peyote? - ✔✔Peyote is a small, spineless cactus, and has a
mescaline which causes halluciantions
Who invented complexes of arsenic and organic molecules which later led
to the cure for Syplihlis in 1900s - ✔✔Paul Ehrlich
who introduced sulfa drugs in 1930s - ✔✔Gerhard Domagk
Who created penicillin in 1940s - ✔✔Alexander Fleming
Who created streptomycin in 1950s - ✔✔Selman Waksman
,©NINJANERD 2024/2025. YEAR PUBLISHED 2024.
What are the 5 steps of drug development - ✔✔Basic research, Preclinical
trials, Clinical trials, Health Canada review and manufacturing, and post
market surveillance and phase IV clinical trial
What 2 parts are in basic research and drug discovery - ✔✔Identification of
target, and studying the target
What are the 2 types of preclinical trials - ✔✔Toxicology studies, and
pharmacology studies
What 3 things are a part of clinical trials? - ✔✔Proof of safety,
Methodology, and investigation
What are the 3 pahses of clinical trials - ✔✔Phase 1 - lookds at ADME in
small group
Phase 2 - looks at patients to see effects in medium sized group
Phase 3 - RCT with 1000's of people
What is a gold standard drug? - ✔✔A drug which is the current treatment
for a condition
Why is it safe to take a drug which was just rebranded? - ✔✔The rebrand
drug and original must be bioequivalent which basically means the same.
The only thing that changes is the name.
, ©NINJANERD 2024/2025. YEAR PUBLISHED 2024.
Why are post-market surveillance and phase IV clinical trials so important -
✔✔Helps identify and new side effects specific to certain people.
What are drug targets? - ✔✔Usually receptors and drug goes towards this
thing to produce an effect as either an agonist or antagonist
What is an agonist? - ✔✔It is a drug that is capable of binding to, and
activating, a receptor
What is an antagonist? - ✔✔They block the action of an agonist getting to
the receptor to elicit a response, therefore no response is made
What is the efficacy of a drug? - ✔✔the maximal response produced by the
drug
How is efficacy different from potency? - ✔✔Potency is the amount of a
substance needed to give a response, while efficacy is the max response
What is ED50? - ✔✔effective dose for 50% of the population
What has a greater efficacy, morphine or aspirin? - ✔✔Morphine since it
has a higher maximum effect
What is the therapeutic range? - ✔✔The range where the drug is above the
minimum concentration for an effect but below the maximum which would
produce a toxic effect
What is ADME - ✔✔absorption, distribution, metabolism, excretion
PHAR 100 Exam Questions and Answers
100% Solved | Graded A+
What 3 civilizations were mentioned in the module about the history of
drugs and what drug was associated with them? - ✔✔Ancient Greece
(opium and codeine), Ancient China (ma Huang), and Ancient Egypt
(purgatives)
What poisons were mentioned in the module? - ✔✔Curare and Ergot
What is peyote? - ✔✔Peyote is a small, spineless cactus, and has a
mescaline which causes halluciantions
Who invented complexes of arsenic and organic molecules which later led
to the cure for Syplihlis in 1900s - ✔✔Paul Ehrlich
who introduced sulfa drugs in 1930s - ✔✔Gerhard Domagk
Who created penicillin in 1940s - ✔✔Alexander Fleming
Who created streptomycin in 1950s - ✔✔Selman Waksman
,©NINJANERD 2024/2025. YEAR PUBLISHED 2024.
What are the 5 steps of drug development - ✔✔Basic research, Preclinical
trials, Clinical trials, Health Canada review and manufacturing, and post
market surveillance and phase IV clinical trial
What 2 parts are in basic research and drug discovery - ✔✔Identification of
target, and studying the target
What are the 2 types of preclinical trials - ✔✔Toxicology studies, and
pharmacology studies
What 3 things are a part of clinical trials? - ✔✔Proof of safety,
Methodology, and investigation
What are the 3 pahses of clinical trials - ✔✔Phase 1 - lookds at ADME in
small group
Phase 2 - looks at patients to see effects in medium sized group
Phase 3 - RCT with 1000's of people
What is a gold standard drug? - ✔✔A drug which is the current treatment
for a condition
Why is it safe to take a drug which was just rebranded? - ✔✔The rebrand
drug and original must be bioequivalent which basically means the same.
The only thing that changes is the name.
, ©NINJANERD 2024/2025. YEAR PUBLISHED 2024.
Why are post-market surveillance and phase IV clinical trials so important -
✔✔Helps identify and new side effects specific to certain people.
What are drug targets? - ✔✔Usually receptors and drug goes towards this
thing to produce an effect as either an agonist or antagonist
What is an agonist? - ✔✔It is a drug that is capable of binding to, and
activating, a receptor
What is an antagonist? - ✔✔They block the action of an agonist getting to
the receptor to elicit a response, therefore no response is made
What is the efficacy of a drug? - ✔✔the maximal response produced by the
drug
How is efficacy different from potency? - ✔✔Potency is the amount of a
substance needed to give a response, while efficacy is the max response
What is ED50? - ✔✔effective dose for 50% of the population
What has a greater efficacy, morphine or aspirin? - ✔✔Morphine since it
has a higher maximum effect
What is the therapeutic range? - ✔✔The range where the drug is above the
minimum concentration for an effect but below the maximum which would
produce a toxic effect
What is ADME - ✔✔absorption, distribution, metabolism, excretion
