Galen Pharmacology Test 1
protein binding - ✔️✔️protein (usually albumin) binds to medication to help chemicals
move through. When the medication is bound to the protein it is not available to perform
its action the body
antacids drug absorption - ✔️✔️Antacids cause a pharmokinetic interaction which is
what the body does to the drug in terms of absorption, distribution, metabolism, and
excretion. Antacids increase the PH of gastric juices which causes a decrease in the
absorption of weak acid drugs such as tetracycline
ear drops - ✔️✔️INSTILL AT ROOM TEMP/ child- down and back/ adult- up and back
eye drops - ✔️✔️important to instill the eye drop medication into the conjunctival sac
(not the eyeball/cornea). inner to outer
enema - ✔️✔️patient lays on left side
pharmacokinetic - ✔️✔️what happens in the body once med is administered
-Absorption
-Distribution/ Binding
-Metabolism
-Renal Excretion
first-pass effect - ✔️✔️extent to which drug metabolized by liver before reaching
systemic circulation
free drug - ✔️✔️The amount that is left not bound called the__________________and
it performs the pharmacologic response
pharmacodynamics phase - ✔️✔️refers to the effects drugs will have on a patient and
the mechanism of their actions.
gastric and intestinal motility influence drug absorption. - ✔️✔️Drug absorption is the
movement of the drug into the bloodstream after administration (McCuistion & Vuljoin-
Dimmagio, 2018, p. 16). The lining of the small intestine is covered in villi that increase
the the surface area for absorption and is decreased because of disease or drugs
(p.16). Absorption in the small intestine is done by passive transport, active transport, or
pinocytosis (p.16). In the GI tract the lining is made up of a mucous membrane
composes of lipids and proteins which allows lipid soluble drugs to easily pass through
protein binding - ✔️✔️protein (usually albumin) binds to medication to help chemicals
move through. When the medication is bound to the protein it is not available to perform
its action the body
antacids drug absorption - ✔️✔️Antacids cause a pharmokinetic interaction which is
what the body does to the drug in terms of absorption, distribution, metabolism, and
excretion. Antacids increase the PH of gastric juices which causes a decrease in the
absorption of weak acid drugs such as tetracycline
ear drops - ✔️✔️INSTILL AT ROOM TEMP/ child- down and back/ adult- up and back
eye drops - ✔️✔️important to instill the eye drop medication into the conjunctival sac
(not the eyeball/cornea). inner to outer
enema - ✔️✔️patient lays on left side
pharmacokinetic - ✔️✔️what happens in the body once med is administered
-Absorption
-Distribution/ Binding
-Metabolism
-Renal Excretion
first-pass effect - ✔️✔️extent to which drug metabolized by liver before reaching
systemic circulation
free drug - ✔️✔️The amount that is left not bound called the__________________and
it performs the pharmacologic response
pharmacodynamics phase - ✔️✔️refers to the effects drugs will have on a patient and
the mechanism of their actions.
gastric and intestinal motility influence drug absorption. - ✔️✔️Drug absorption is the
movement of the drug into the bloodstream after administration (McCuistion & Vuljoin-
Dimmagio, 2018, p. 16). The lining of the small intestine is covered in villi that increase
the the surface area for absorption and is decreased because of disease or drugs
(p.16). Absorption in the small intestine is done by passive transport, active transport, or
pinocytosis (p.16). In the GI tract the lining is made up of a mucous membrane
composes of lipids and proteins which allows lipid soluble drugs to easily pass through
