NBME 28 Exam Questions and Answers
Which iisensory iiinformation iiis iicompromised iiby iithe iianterior iilobe iiof iithe iisuperior
iicerebellum? ii- iiAnswers ii-unconscious iiproprioception
What iicontrols iiconscious iiproprioception? ii- iiAnswers ii-DCML
Lesion iiin iithis iipart iiof iithe iicerebellum iican iicause iibroad iibased iiataxia ii- iiAnswers ii-
anterior iilobe
Conscious iiproprioception, ii2 iipoint iidiscrimination iiand ii_______ iiis iialso iimediated iiby
iithe iiDMCL ii- iiAnswers ii-vibration iisense
Synthesis iiof iienzymes iinecessary iifor iireplication iiof iigenome iioccurs iiin iiwhich iiphase
iiof iithe iicell iicycle? ii- iiAnswers ii-G1 ii(because iiDNA iigets iiduplicated iiafter iiin iiS iiphase)
Does iiproteins iisynthesis iioccur iiin iiM iiphase? ii- iiAnswers ii-no
This iiis iithe iiphase iiof iicell iiwhere iiDNA iireplication iioccurs ii- iiAnswers ii-S iiphase
This iiis iithe iiphase iiwhere iiintegrity iiof iiduplicated iigenome iiis iichecked iiand iicorrected.
ii- iiAnswers ii-G2
G2 iiphase iiis iialso iiwhere iiphase iiof iigrowth iiand ii________ iisynthesis iitakes iiplace iiin
iipreparation iifor iithe iiphases iiof iimitosis iiand iicell iidivision ii- iiAnswers ii-protein
When iilooking iiat iia iiserum ii[PAH] iivs. iiPAH iisecretion iirate iigraph, iithere iiis iian
iiinflection iipoint iiwhere iisecretion iirate iiplateaus, iiwhich iimeans iithe iiclearance iiof iiPAH
iidoes iinot iiincrease ii(slope ii0). ii
Before iithis iiinflection iipoint, iithe iiclearance iiof iiPAH iiis iihigher ii(slope ii>0). ii
This iimeans iithat iion iithe iiplateau iiarea, iiPAH iiclearance iiis ii______ iithan iiit iiis iiin iithe
iiascending iiarea. ii- iiAnswers ii-lower
What iisequence iiencods iithe iipolyadenylation iisignal? ii- iiAnswers ii-AATAAA
Where iido iisplice iisites iiexist? ii- iiAnswers ii-At iithe iiend iiof iian iiintron iiand iibeginning iiof
iian iiexon
Mutations iiin iithe ii_____ iiregion iiare iiknown iito iicause iibeta iithalassemia. ii- iiAnswers ii-
promoter
, Capping iiwith iiGTP iioccurs iiat iithe iibeginning iiof iitrasncription iiat iithe ii________. ii-
iiAnswers ii-5' iiend iiof iithe iinascent iimRNA
Capping iiwith iiGTP iiat iithe ii5' iiend iiof iinascent iimRNA iiis iirecognized iiby ii______ iiin
iicytoplasm iiand iifacilitates iiinitation iiof iitranslation. ii- iiAnswers ii-ribosomes
A iimutation iiin iiGTP iicap iiwould iiresult iiin iisynthesis iiof iinormal iimRNA iitranscript iibut
iifailure iiof ii_________. ii- iiAnswers ii-translation
A ii5 iiyr iiold iigirl iihas iiprecocious iipuberty. iiPelvic iiexam iishows iia iimass iiconsistent iiwith
iiovarian iitumor. iiSstudies iishow iidecreased iigonadotropins iiand iimarked iiincrease iiin
iiestrogens.
What iiis iithe iiovarian iitumor iiderived iifrom iimost iilikely? ii- iiAnswers ii-Granulosa
_____ iitumors iialso iiproduce iiestrogen iiand iiandrogen iilike iigranulosa iitumors iiand iimay
iipresent iiwith iipostmenopausal iibleeding iibut iiare iiless iicommon iithan iigranulosa
iitumors. ii- iiAnswers ii-thecal
An iiold iipatient iiwith iifever, iichills, iitachycardia, iihypotension iiand iifinally iishock iigrows
iiE. iicoli.
What iiis iithe iimost iilikely iiinitial iicause iiof iithe iihypotension? ii- iiAnswers ii-Excessive
iiproduction iiof iinitric iioxide
Note iithat iithis iiis iinot iicaused iiby iihemorrhage iibecause iiour iipatient's iiabdominal iipain
iiis iimost iilikely iid/t iiinfectious iienteritis iiand iiless iilikely iifrom iian iiabdominal iiaortic
iianeurysm.
Ganciclovir iiis iia iiguanosine iianalog iithat iitreats iiCMV iiand iiinhibits iiwhat? ii- iiAnswers ii-
DNA iipolymerase
Acyclovir, iivalacyclovir, iiand iifamciclovir iitreats iiHSV iiby iiinhibiting? ii- iiAnswers ii-
thymidine iikinase
Is iiacyclovir iiused iito iitreat iiCMV? ii- iiAnswers ii-No; iibecause iiCMV iidoes iinot iihave
iithymidine iikinase
Which iimuscle iisupinates iithe iiforearm? ii- iiAnswers ii-biceps iibrachii
Biceps iibrachii iiserves iito iisupinate iithe iiforearm iithrough iiits iiwinding iimechanism
iiaround iithe ii_________ ii_____ iiand iibicipital iituberosity ii- iiAnswers ii-proximal iiradius
Which iisensory iiinformation iiis iicompromised iiby iithe iianterior iilobe iiof iithe iisuperior
iicerebellum? ii- iiAnswers ii-unconscious iiproprioception
What iicontrols iiconscious iiproprioception? ii- iiAnswers ii-DCML
Lesion iiin iithis iipart iiof iithe iicerebellum iican iicause iibroad iibased iiataxia ii- iiAnswers ii-
anterior iilobe
Conscious iiproprioception, ii2 iipoint iidiscrimination iiand ii_______ iiis iialso iimediated iiby
iithe iiDMCL ii- iiAnswers ii-vibration iisense
Synthesis iiof iienzymes iinecessary iifor iireplication iiof iigenome iioccurs iiin iiwhich iiphase
iiof iithe iicell iicycle? ii- iiAnswers ii-G1 ii(because iiDNA iigets iiduplicated iiafter iiin iiS iiphase)
Does iiproteins iisynthesis iioccur iiin iiM iiphase? ii- iiAnswers ii-no
This iiis iithe iiphase iiof iicell iiwhere iiDNA iireplication iioccurs ii- iiAnswers ii-S iiphase
This iiis iithe iiphase iiwhere iiintegrity iiof iiduplicated iigenome iiis iichecked iiand iicorrected.
ii- iiAnswers ii-G2
G2 iiphase iiis iialso iiwhere iiphase iiof iigrowth iiand ii________ iisynthesis iitakes iiplace iiin
iipreparation iifor iithe iiphases iiof iimitosis iiand iicell iidivision ii- iiAnswers ii-protein
When iilooking iiat iia iiserum ii[PAH] iivs. iiPAH iisecretion iirate iigraph, iithere iiis iian
iiinflection iipoint iiwhere iisecretion iirate iiplateaus, iiwhich iimeans iithe iiclearance iiof iiPAH
iidoes iinot iiincrease ii(slope ii0). ii
Before iithis iiinflection iipoint, iithe iiclearance iiof iiPAH iiis iihigher ii(slope ii>0). ii
This iimeans iithat iion iithe iiplateau iiarea, iiPAH iiclearance iiis ii______ iithan iiit iiis iiin iithe
iiascending iiarea. ii- iiAnswers ii-lower
What iisequence iiencods iithe iipolyadenylation iisignal? ii- iiAnswers ii-AATAAA
Where iido iisplice iisites iiexist? ii- iiAnswers ii-At iithe iiend iiof iian iiintron iiand iibeginning iiof
iian iiexon
Mutations iiin iithe ii_____ iiregion iiare iiknown iito iicause iibeta iithalassemia. ii- iiAnswers ii-
promoter
, Capping iiwith iiGTP iioccurs iiat iithe iibeginning iiof iitrasncription iiat iithe ii________. ii-
iiAnswers ii-5' iiend iiof iithe iinascent iimRNA
Capping iiwith iiGTP iiat iithe ii5' iiend iiof iinascent iimRNA iiis iirecognized iiby ii______ iiin
iicytoplasm iiand iifacilitates iiinitation iiof iitranslation. ii- iiAnswers ii-ribosomes
A iimutation iiin iiGTP iicap iiwould iiresult iiin iisynthesis iiof iinormal iimRNA iitranscript iibut
iifailure iiof ii_________. ii- iiAnswers ii-translation
A ii5 iiyr iiold iigirl iihas iiprecocious iipuberty. iiPelvic iiexam iishows iia iimass iiconsistent iiwith
iiovarian iitumor. iiSstudies iishow iidecreased iigonadotropins iiand iimarked iiincrease iiin
iiestrogens.
What iiis iithe iiovarian iitumor iiderived iifrom iimost iilikely? ii- iiAnswers ii-Granulosa
_____ iitumors iialso iiproduce iiestrogen iiand iiandrogen iilike iigranulosa iitumors iiand iimay
iipresent iiwith iipostmenopausal iibleeding iibut iiare iiless iicommon iithan iigranulosa
iitumors. ii- iiAnswers ii-thecal
An iiold iipatient iiwith iifever, iichills, iitachycardia, iihypotension iiand iifinally iishock iigrows
iiE. iicoli.
What iiis iithe iimost iilikely iiinitial iicause iiof iithe iihypotension? ii- iiAnswers ii-Excessive
iiproduction iiof iinitric iioxide
Note iithat iithis iiis iinot iicaused iiby iihemorrhage iibecause iiour iipatient's iiabdominal iipain
iiis iimost iilikely iid/t iiinfectious iienteritis iiand iiless iilikely iifrom iian iiabdominal iiaortic
iianeurysm.
Ganciclovir iiis iia iiguanosine iianalog iithat iitreats iiCMV iiand iiinhibits iiwhat? ii- iiAnswers ii-
DNA iipolymerase
Acyclovir, iivalacyclovir, iiand iifamciclovir iitreats iiHSV iiby iiinhibiting? ii- iiAnswers ii-
thymidine iikinase
Is iiacyclovir iiused iito iitreat iiCMV? ii- iiAnswers ii-No; iibecause iiCMV iidoes iinot iihave
iithymidine iikinase
Which iimuscle iisupinates iithe iiforearm? ii- iiAnswers ii-biceps iibrachii
Biceps iibrachii iiserves iito iisupinate iithe iiforearm iithrough iiits iiwinding iimechanism
iiaround iithe ii_________ ii_____ iiand iibicipital iituberosity ii- iiAnswers ii-proximal iiradius
