MCB Exam 2 - RATs (5-9) Questions with
100% Correct Answers
in euk cells the factors that are involved in the most mRNAs are known as -
✔✔general transcription factors
the first phosphorylation event affecting the CTD of the large subunit of ___
is mediated by a kinase activity assoc. to ___ - ✔✔RNA pol II; TFIIH
in euk cells the RNA pol that transcribes messenger RNA is ___ - ✔✔RNA
pol II
one striking diff at the level in which transcription is initiated btw prok and
euk is that - ✔✔in prok all factors required to start transcription are
associated to the holo-enzyme, whereas in euk additional protein factors
besides the RNA pol are needed to initiate transcription
the TFII factor that bridges the interaction btw TFIID to the promoter and
positioning it in place to initiate transcription is ___ - ✔✔TFIIB
The TFII factor that contains among its subunits two proteins known as
XPD and XPB each endowed with helicase activity is ___ - ✔✔TFIIH
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the helicase activity that allows transcription by RNA pol II to start is
mediated by - ✔✔TFIIH
evolutionarily speaking the existence in euk of three diff polymerases is
most likely the result of - ✔✔a selective pressure to ensure high expression
of a specific set of genes while allowing tight control of others
phosphorylation of the CTD is a key regulatory event during transcriptional
initiation by RNA pol I - ✔✔False
in euk cells transcription of the genes coding for the large ribosomal RNAs
yields a large 45S pre-rRNA that is later on processed to produce the 18S,
5.8S, and 5S rRNAs - ✔✔false
histone deacetylases could be argued to typically ___ gene expression -
✔✔decrease
the essential sequence that drives the recruitment of general transcription
factors thus allowing transcription to occur is known as the - ✔✔Core
promoter (?)
these are sequences that divide chromosomes into independent domains
and prevent enhancers form acting on promoters located on a different
domain - ✔✔insulators