systemic lupus erythematosus (SLE) Correct Answer-Autoimmune
disease in which immune system attacks connective tissue throughout
body such as in joints and skin.
Chronic multisystem inflammatory autoimmune disorder.
SLE is more common in: Correct Answer-Females (85%)
Higher incidence in young women of color in the US.
Common clinical findings with SLE: Correct Answer-Fatigue, joint
pain, rash, seizures, chest pain, vasculitis, nephritis, weight loss, fevers,
tachycardia, lymphadenopathy
discoid lupus erythematosus Correct Answer-Rash primarily seen on the
face, scalp and trunk. Aggravated by the sun.
Malar butterfly rash seen in: Correct Answer-SLE
SLE workup may include: Correct Answer-CBC, ESR, CRP, Gamma
Globulins, ANA, RA, Anti-Smith, BUN/Creat, 24 hour protein, IgG,
IgM, Anti-beta 2 glycoprotein
,Lupus nonpharmacologic management: Correct Answer-Heart health
diet, modest exercise, avoidance of sun
Lupus pharmacologic management: Correct Answer-Omega-3
Steroids
NSAIDS
Hydrochloroquine
Monoclonal Antibody
Immunosuppressants
Raynaud's disease Correct Answer-Peripheral arterial occlusive disease
in which intermittent attacks are triggered by cold or stress.
Raynaud's Disease Correct Answer-Reversible vasospastic disorder that
affects the blood flow to the digits.
Raynaud's generally affects: Correct Answer-Females
(Often presents 15-45 years of age)
_______- Raynaud's Phenomenon:
No associated autoimmune disease. No autoantibodies present. Correct
Answer-Primary
______ Raynaud's Phenomenon:
, Associated with an autoimmune disease. (SLE, Scleroderma, mixed
connective tissue disease) Correct Answer-Secondary
CREST syndrome ("systemic sclerosis") Correct Answer-Calcinosis
Raynaud's
Esophageal dysmotility
Sclerodactyly (skin tightening on hands)
Telangiectasia (capillary dilation on - red spots on skin)
______ Raynaud's Phenomenon may be associated with CREST
syndrome. Correct Answer-Secondary
Individual's with Raynaud's Phenomenon may also experience: (3)
Correct Answer-Migraines, headaches, chest pain
Raynaud's Phenomenon may be related to: Correct Answer-Drugs,
trauma, hematologic disorders, vibrations, frostbite, atherosclerotic
disease
Sharp demarcation where the spasm occurs.
Tricolor presentation of Raynaud's Phenomenon:
___ --> _____ -->_____ Correct Answer-Pallor --> Cyanosis --> Rubor
Raynaud's is often triggered by: ___ or ____ Correct Answer-Cold
exposure or stress