Pathoma Chapter 7- Questions and Answers 100%
Solved
What artery involvement causes visual disturbances and headache in Temporal (Giant Cell)
Arteritis Correct Ans-Visual: opthalmic artery involvement
Headache: temporal artery involvement
What is the joint and muscle pain that can be present in Temporal (Giant Cell) Arteritis called
Correct Ans-Polymyalgia rheumatica
Biopsy of Temporal (Giant Cell) Arteritis Correct Ans-Inflamed vessel with giant cells and
intimal fibrosis with segmental lesions
What does diagnosis of Temporal (Giant Cell) Arteritis require on biopsy? Correct Ans-
Biopsy of long segment of vessel
Does a negative biopsy for Temporal (Giant Cell) Arteritis exclude disease? Correct Ans-No
Treatment of Temporal (Giant Cell) Arteritis and risk without treatment Correct Ans-
Treatment: corticosteroids
Risk of no treatment: blindness
Granulomatous vasculitis that involves the aortic arch at branch points Correct Ans-
Takayasu Arteritis
, Pathoma Chapter 7- Questions and Answers 100%
Solved
Granulomatous vasculitis that typically involves branches of the carotid artery Correct Ans-
Temporal (Giant Cell) Vasculitis
How does Takayasu Arteritis present Correct Ans-Visual and neurologic symptosm witha
weak or absent pulse in upper extremity; elevated ESR
Pulseless disease Correct Ans-Takayasu Arteritis
Who is affected by Takayasu Arteritis most often? Correct Ans-Adults younger than 50,
typically young Asian Females
Treatment of Takayasu Arteritis Correct Ans-Corticosteroids
Age of presentation of Takayasu Arteritis versus Temporal (Giant Cell) Arteritis Correct Ans-
Takayasu Arteritis: less than 50 (young Asian females)
Temporal (Giant Cell) Arteritis: older than 50 (females)
Name the three medium vessel vasculitides Correct Ans-Polyarteritis Nodosa
Kawasaki Disease
Buerger Disease
, Pathoma Chapter 7- Questions and Answers 100%
Solved
Medium-vessel necrotizing vasculitis involving multiple organs, but sparing the lungs
Correct Ans-Polyarteritis Nodosa
Inflammation of blood vessel wall (either artery or vein) Correct Ans-Vasculitis
What are the three layers of the arterial wall? Correct Ans-Endothelial intima, smooth
muscle media, connective tissue adventitia
Normal muscular artery Correct Ans-Intima (innermost), media, and adventitia layer
What is the cause of vasculitis? Correct Ans-Etiology unknown, but not infectious usually
Name two clinical features of vasculitis Correct Ans-1. Nonspecific symptoms of
inflammation (fever, fatigue, weight loss, myalgias)
2. Symptoms of organ ischemia
What causes symptoms of organ ischemia in vasculitis? Correct Ans-Luminal narrowing or
thrombosis of the inflamed vessel
What are the three types of vasculitides? Correct Ans-Large, medium, and small
What does large vessel vasculitis involve? Correct Ans-Aorta and its major branches
, Pathoma Chapter 7- Questions and Answers 100%
Solved
What does medium vessel vasculitis involve? Correct Ans-Muscular arteries that supply
organs
What does small vessel vasculitis involve? Correct Ans-Arteries, capillaries, venules
Name the two types of large vessel vasculitis Correct Ans-Temporal (Giant Cell) Arteritis
Takayasu Arteritis
What vessel does Temporal (Giant Cell) Arteritis typically involve? Correct Ans-Branches of
carotid
Granulomatous vasculitis Correct Ans-Temporal (Giant Cell) Arteritis
Takayasu Arteritis
Wegner's
Churg-Strauss
Who is affected by Temporal (Giant Cell) Arteritis Correct Ans-Older adults (over 50)
Usually female
Solved
What artery involvement causes visual disturbances and headache in Temporal (Giant Cell)
Arteritis Correct Ans-Visual: opthalmic artery involvement
Headache: temporal artery involvement
What is the joint and muscle pain that can be present in Temporal (Giant Cell) Arteritis called
Correct Ans-Polymyalgia rheumatica
Biopsy of Temporal (Giant Cell) Arteritis Correct Ans-Inflamed vessel with giant cells and
intimal fibrosis with segmental lesions
What does diagnosis of Temporal (Giant Cell) Arteritis require on biopsy? Correct Ans-
Biopsy of long segment of vessel
Does a negative biopsy for Temporal (Giant Cell) Arteritis exclude disease? Correct Ans-No
Treatment of Temporal (Giant Cell) Arteritis and risk without treatment Correct Ans-
Treatment: corticosteroids
Risk of no treatment: blindness
Granulomatous vasculitis that involves the aortic arch at branch points Correct Ans-
Takayasu Arteritis
, Pathoma Chapter 7- Questions and Answers 100%
Solved
Granulomatous vasculitis that typically involves branches of the carotid artery Correct Ans-
Temporal (Giant Cell) Vasculitis
How does Takayasu Arteritis present Correct Ans-Visual and neurologic symptosm witha
weak or absent pulse in upper extremity; elevated ESR
Pulseless disease Correct Ans-Takayasu Arteritis
Who is affected by Takayasu Arteritis most often? Correct Ans-Adults younger than 50,
typically young Asian Females
Treatment of Takayasu Arteritis Correct Ans-Corticosteroids
Age of presentation of Takayasu Arteritis versus Temporal (Giant Cell) Arteritis Correct Ans-
Takayasu Arteritis: less than 50 (young Asian females)
Temporal (Giant Cell) Arteritis: older than 50 (females)
Name the three medium vessel vasculitides Correct Ans-Polyarteritis Nodosa
Kawasaki Disease
Buerger Disease
, Pathoma Chapter 7- Questions and Answers 100%
Solved
Medium-vessel necrotizing vasculitis involving multiple organs, but sparing the lungs
Correct Ans-Polyarteritis Nodosa
Inflammation of blood vessel wall (either artery or vein) Correct Ans-Vasculitis
What are the three layers of the arterial wall? Correct Ans-Endothelial intima, smooth
muscle media, connective tissue adventitia
Normal muscular artery Correct Ans-Intima (innermost), media, and adventitia layer
What is the cause of vasculitis? Correct Ans-Etiology unknown, but not infectious usually
Name two clinical features of vasculitis Correct Ans-1. Nonspecific symptoms of
inflammation (fever, fatigue, weight loss, myalgias)
2. Symptoms of organ ischemia
What causes symptoms of organ ischemia in vasculitis? Correct Ans-Luminal narrowing or
thrombosis of the inflamed vessel
What are the three types of vasculitides? Correct Ans-Large, medium, and small
What does large vessel vasculitis involve? Correct Ans-Aorta and its major branches
, Pathoma Chapter 7- Questions and Answers 100%
Solved
What does medium vessel vasculitis involve? Correct Ans-Muscular arteries that supply
organs
What does small vessel vasculitis involve? Correct Ans-Arteries, capillaries, venules
Name the two types of large vessel vasculitis Correct Ans-Temporal (Giant Cell) Arteritis
Takayasu Arteritis
What vessel does Temporal (Giant Cell) Arteritis typically involve? Correct Ans-Branches of
carotid
Granulomatous vasculitis Correct Ans-Temporal (Giant Cell) Arteritis
Takayasu Arteritis
Wegner's
Churg-Strauss
Who is affected by Temporal (Giant Cell) Arteritis Correct Ans-Older adults (over 50)
Usually female
