BCH EXAM 2 PRACTICE
Which of the following curves shows the appropriate relationship between [ES] and time in steady state
kinetics? - correct answer ✔✔C) (c)
Which of the following would represent the reaction coordinate for a two-step reaction with an initial
slow
step? - correct answer ✔✔A) A
Which of the following amino acids could bind to the specificity pocket of Trypsin? - correct answer
✔✔B) Lys
The chymotrypsin/trypsin family of proteases has which combination of amino acids in the active site -
correct answer ✔✔D) serine, histidine, aspartic acid
Which of the following would be a proper representation of enzyme velocity? - correct answer ✔✔E)
Either B or C
The rate constant associated with the reaction below would be
2A --> B - correct answer ✔✔C) Second order
Which type of secondary structure present in integral membrane proteins is readily detectable in the
primary structure? - correct answer ✔✔A) membrane-spanning α helix
Which of the following lipid types are not found in animal membranes? - correct answer ✔✔C)
triacylglycerols
A molecule moves across a membrane from a lower to a higher concentration with the aid of a
membrane protein. This process is known as: - correct answer ✔✔C) active transport
, Which of the following will cause the opening or closing of a gated ion channel? - correct answer ✔✔E)
all of the above
Which amino acid in the aquaporin channel hydrogen bonds with water to prevent the movement of
protons? - correct answer ✔✔A) Asn
Which of the following second messengers would NOT be found free floating in the cytosol? - correct
answer ✔✔A) DAG
Acetylcholine and nicotine competitively bind to nicotinic acetylcholine receptors to cause the same
second messenger activation. Nicotine is considered an _______________ of the receptors. - correct
answer ✔✔A) agonist
The complex formed between a lipid hormone and its receptor binds to _____ which are specific DNA
sequences. - correct answer ✔✔D) hormone response elements
Hexokinase undergoes a large conformational change in order to exclude water from the active site.
Would chymotrypsin undergo such a change upon binding its substrate? - correct answer ✔✔B) No
In the reaction mechanism of the glycolytic enzyme aldolase, an active site tyrosine residue accepts a
proton from the substrate. In this form the side chain of Tyr must be _________ and it is acting as a(n)
__________ catalyst. - correct answer ✔✔C) deprotonated; base
Based on the reaction below, how would the enzyme catalyzing this reaction be classified? - correct
answer ✔✔E) Transferase
A patient suffers from premature zymogen activation, so that the pancreatic enzymes are activated in
the pancreas rather than the small intestine -- causing damage to the pancreas. Which of the following
would be the most effective in preventing these effects? - correct answer ✔✔B) trypsin inhibitor
Which of the following is FALSE regarding transition state stabilization? - correct answer ✔✔C) Transition
state stabilization refers to the shift in the equilibrium of the reaction
Which of the following curves shows the appropriate relationship between [ES] and time in steady state
kinetics? - correct answer ✔✔C) (c)
Which of the following would represent the reaction coordinate for a two-step reaction with an initial
slow
step? - correct answer ✔✔A) A
Which of the following amino acids could bind to the specificity pocket of Trypsin? - correct answer
✔✔B) Lys
The chymotrypsin/trypsin family of proteases has which combination of amino acids in the active site -
correct answer ✔✔D) serine, histidine, aspartic acid
Which of the following would be a proper representation of enzyme velocity? - correct answer ✔✔E)
Either B or C
The rate constant associated with the reaction below would be
2A --> B - correct answer ✔✔C) Second order
Which type of secondary structure present in integral membrane proteins is readily detectable in the
primary structure? - correct answer ✔✔A) membrane-spanning α helix
Which of the following lipid types are not found in animal membranes? - correct answer ✔✔C)
triacylglycerols
A molecule moves across a membrane from a lower to a higher concentration with the aid of a
membrane protein. This process is known as: - correct answer ✔✔C) active transport
, Which of the following will cause the opening or closing of a gated ion channel? - correct answer ✔✔E)
all of the above
Which amino acid in the aquaporin channel hydrogen bonds with water to prevent the movement of
protons? - correct answer ✔✔A) Asn
Which of the following second messengers would NOT be found free floating in the cytosol? - correct
answer ✔✔A) DAG
Acetylcholine and nicotine competitively bind to nicotinic acetylcholine receptors to cause the same
second messenger activation. Nicotine is considered an _______________ of the receptors. - correct
answer ✔✔A) agonist
The complex formed between a lipid hormone and its receptor binds to _____ which are specific DNA
sequences. - correct answer ✔✔D) hormone response elements
Hexokinase undergoes a large conformational change in order to exclude water from the active site.
Would chymotrypsin undergo such a change upon binding its substrate? - correct answer ✔✔B) No
In the reaction mechanism of the glycolytic enzyme aldolase, an active site tyrosine residue accepts a
proton from the substrate. In this form the side chain of Tyr must be _________ and it is acting as a(n)
__________ catalyst. - correct answer ✔✔C) deprotonated; base
Based on the reaction below, how would the enzyme catalyzing this reaction be classified? - correct
answer ✔✔E) Transferase
A patient suffers from premature zymogen activation, so that the pancreatic enzymes are activated in
the pancreas rather than the small intestine -- causing damage to the pancreas. Which of the following
would be the most effective in preventing these effects? - correct answer ✔✔B) trypsin inhibitor
Which of the following is FALSE regarding transition state stabilization? - correct answer ✔✔C) Transition
state stabilization refers to the shift in the equilibrium of the reaction
