NEONATAL HEMATOLOGY EXAM
QUESTIONS WITH COMPLETE
ANSWERS { GRADED A+}
Delivers O2 from lungs to tissues - ✔✔hemoglobin
fetal Hgb is a major component by _____ wks gestation - ✔✔10
transition begins at end of fetal life; RBCs contain ______% of HgbF at
birth - ✔✔70-90%
fetal Hgb has increased affinity for oxygen which results in increase or
decreased O2 release to tissues? - ✔✔decreased - blue baby at birth!!
T/F? Hct values increase immediately after birth - ✔✔TRUE
,formation, production, and maintenance of blood cells -
✔✔hematopoiesis
Where does hematopoiesis occur in the fetus? - ✔✔yolk sac (3-6 wks)
liver (6-16 wks)
bone marrow (predominates after 22-24 wks)
production of erythrocytes (RBCs) - ✔✔erythropoiesis
erythropoiesis is increased in response to? - ✔✔anemia and low oxygen
Erythropoiesis and synthesis of hemoglobin are regulated by the
hormone? - ✔✔erythropoietin
erythropoietin production is increase in response to ______ and
______ and decreased in response to ______ - ✔✔anemia and low
oxygen availability
hypertransfusion
, low oxygen pressure causes the kidneys and liver to release
erythropoietin which stimulates the production of RBC that carry
oxygen to the tissues increasing the oxygen carrying capacity; once the
oxygen carrying capacity is increased, the production of erythropoietin
is inhibited- this is called? - ✔✔negative feedback loop
_______ cause hematopoietic stem cell to become any formed cell
needed - ✔✔colony stimulating factors
Sites of extramedullary hematopoiesis which are _______ aid
production of cells during fetal life when long bones are small -
✔✔liver, spleen, thymus, kidneys
What are RBC function? - ✔✔tissue oxygenation by Hgb transport
CO2 removal through reaction with carbonic anhydrase
Hgb can serve as a buffer to maintain acid-base balance
life span of RBC in adult, term infant, preterm infant? - ✔✔adult: 100-
120 days
QUESTIONS WITH COMPLETE
ANSWERS { GRADED A+}
Delivers O2 from lungs to tissues - ✔✔hemoglobin
fetal Hgb is a major component by _____ wks gestation - ✔✔10
transition begins at end of fetal life; RBCs contain ______% of HgbF at
birth - ✔✔70-90%
fetal Hgb has increased affinity for oxygen which results in increase or
decreased O2 release to tissues? - ✔✔decreased - blue baby at birth!!
T/F? Hct values increase immediately after birth - ✔✔TRUE
,formation, production, and maintenance of blood cells -
✔✔hematopoiesis
Where does hematopoiesis occur in the fetus? - ✔✔yolk sac (3-6 wks)
liver (6-16 wks)
bone marrow (predominates after 22-24 wks)
production of erythrocytes (RBCs) - ✔✔erythropoiesis
erythropoiesis is increased in response to? - ✔✔anemia and low oxygen
Erythropoiesis and synthesis of hemoglobin are regulated by the
hormone? - ✔✔erythropoietin
erythropoietin production is increase in response to ______ and
______ and decreased in response to ______ - ✔✔anemia and low
oxygen availability
hypertransfusion
, low oxygen pressure causes the kidneys and liver to release
erythropoietin which stimulates the production of RBC that carry
oxygen to the tissues increasing the oxygen carrying capacity; once the
oxygen carrying capacity is increased, the production of erythropoietin
is inhibited- this is called? - ✔✔negative feedback loop
_______ cause hematopoietic stem cell to become any formed cell
needed - ✔✔colony stimulating factors
Sites of extramedullary hematopoiesis which are _______ aid
production of cells during fetal life when long bones are small -
✔✔liver, spleen, thymus, kidneys
What are RBC function? - ✔✔tissue oxygenation by Hgb transport
CO2 removal through reaction with carbonic anhydrase
Hgb can serve as a buffer to maintain acid-base balance
life span of RBC in adult, term infant, preterm infant? - ✔✔adult: 100-
120 days
