PCB 3233 Exam 2
TNF-a - correct answer ✔✔Induces blood vessels to be more permeable, enabling cells, fluid, and
soluble effectors to enter infected tissue
IL-6 - correct answer ✔✔Induces fat and muscle cells to metabolize, generate heat, and raise the
temperature in the infected tissue
CXCL8 - correct answer ✔✔recruits neutrophils from the blood and guides them to the infected tissue
CCL2 - correct answer ✔✔recruits monocytes from the blood and directs them to the infected tissue
IL-12 - correct answer ✔✔recruits and activates NK cells that in turn secrete cytokines that strengthen
the macrophages' response to infection
CR3 and CR4 - correct answer ✔✔Bind iC3b and LPS
Mannose and flu can receptors - correct answer ✔✔Bind to carbohydrates
Scavenger receptors - correct answer ✔✔Recognize negatively charged microbial ligands
CD14 - correct answer ✔✔Bind peptidoglycan, LPS, LTA, and mannuronic acid
TLR4 - correct answer ✔✔Recognizes LPS on bacteria
TLR 3 - correct answer ✔✔Recognizes viral dsRNA
TLR5 - correct answer ✔✔Recognize flagellin on bacteria
TNF-a - correct answer ✔✔Induces blood vessels to be more permeable, enabling cells, fluid, and
soluble effectors to enter infected tissue
IL-6 - correct answer ✔✔Induces fat and muscle cells to metabolize, generate heat, and raise the
temperature in the infected tissue
CXCL8 - correct answer ✔✔recruits neutrophils from the blood and guides them to the infected tissue
CCL2 - correct answer ✔✔recruits monocytes from the blood and directs them to the infected tissue
IL-12 - correct answer ✔✔recruits and activates NK cells that in turn secrete cytokines that strengthen
the macrophages' response to infection
CR3 and CR4 - correct answer ✔✔Bind iC3b and LPS
Mannose and flu can receptors - correct answer ✔✔Bind to carbohydrates
Scavenger receptors - correct answer ✔✔Recognize negatively charged microbial ligands
CD14 - correct answer ✔✔Bind peptidoglycan, LPS, LTA, and mannuronic acid
TLR4 - correct answer ✔✔Recognizes LPS on bacteria
TLR 3 - correct answer ✔✔Recognizes viral dsRNA
TLR5 - correct answer ✔✔Recognize flagellin on bacteria
