PCB 3233 Exam Reviews (1-6)
Which of the following is true about the origins of vaccination? a. The first vaccine was created against
smallpox.
b. The first vaccine was created using the vaccinia virus.
c. The first vaccine was created against variola.
d. A & B
e. A, B & C - correct answer ✔✔E
Commensal species:
a. Typically do not cause harm to the host.
b. Likely become killed off from a round of antibiotics.
c. Can be present in many different parts of the body.
d. A & C
e. A, B & C - correct answer ✔✔E
Which Gram-positive pathogen would be expected to have teichoic acids present in their cell wall?
a. E. coli
d. HIV
b. Staphylococcus
e. Influenza
c. Salmonella - correct answer ✔✔B
4. When is the innate immune system activated?
a. Before the adaptive immune system is activated.
b. Before a pathogen has breached a physical barrier.
c. Only during a secondary immune response (i.e. not during a primary immune response)
d. A & B
,e. B & C - correct answer ✔✔A
5. Which of the following correctly describes inflammation?
a. Inflammation occurs when a pathogen gains entry through a surface wound.
b. Inflammation of the infected tissue typically only results in swelling.
c. Inflammation only results due to infections that are caused by pathogens.
d. Inflammation typically results in decreased vasodilation & decreased vascular permeability.
e. All of the above correctly describes inflammation. - correct answer ✔✔A
Vaccines are efficient in providing protective immunity against a specific pathogen, specifically by
stimulating the adaptive immune response in a manner that results in immunological memory.
a. True
b. False - correct answer ✔✔A
Clonal selection and clonal expansion are both observed in the innate immune response to an infection.
a. True
b. False - correct answer ✔✔B
Lymphocytes are unique in that they only function in adaptive immune responses.
a. True
b. False - correct answer ✔✔B
Which leukocyte, containing cytotoxic granules, would you expect to observe interacting with cells that
are infected with viral particles?
a. Neutrophils
c. Basophils
b. NK cells
d. Eosinophils - correct answer ✔✔B
,The most abundant leukocyte found in the blood are ______, whereas ______ are considered the least
abundant.
a. neutrophils ; lymphocytes
c. lymphocytes ; basophils
b. lymphocytes ; neutrophils
d. neutrophils ; basophils - correct answer ✔✔D
Which of the following immune cells are specialized to capture, engulf, and kill microorganisms? a.
Macrophage
d. A & B
b. Neutrophil
e. A, B & C
c. Monocytes - correct answer ✔✔E
Dendritic cells:
a. Present antigen to T cells to activate them.
b. Can be found in secondary lymphoid tissues.
c. Use only one type of receptor to recognize pathogens.
d. A & B e. A & C - correct answer ✔✔D
B lymphocytes and T lymphocytes both arise in the bone marrow and they both remain there to undergo
their maturation before migrating to organized secondary lymphoid tissues.
a. True
b. False - correct answer ✔✔B
Mast cells:
a. Release histamine and other active contents from their granules.
b. Kill other cells infected with certain viruses.
c. Arise from the myeloid progenitor.
d. A & C
, e. A, B & C - correct answer ✔✔D
Which of the following is true about T-cell receptors?
a. They are highly specific.
b. They are secreted after a T cell has been activated.
c. They are comprised of 4 chains.
d. They can be expressed as a soluble form.
e. All of the above are true. - correct answer ✔✔A
Which of the following pairs is matched incorrectly?
a. Antigen : foreign substance of many different types
b. BCRs : immunoglobulins
c. Helper T cell : kills pathogen-infected cells
d. Plasma cell : involved in antibody secretion
e. T-cell activation : cell division and differentiation are both observed - correct answer ✔✔C
All of the following are examples of secondary lymphoid tissues, except:
a. Bone marrow
d. Peyer's patches
b. Lymph nodes
e. A & B
c. Spleen - correct answer ✔✔A
Which of the following is true about a draining lymph node?
a. It is the site where mature lymphocytes can encounter pathogens.
b. They typically increase in size during an infection.
c. They can be referred to as "swollen gland."
d. It is the site where lymph-borne antigens are encountered by lymphocytes.
e. All of the above are true. - correct answer ✔✔E
Which of the following is true about the origins of vaccination? a. The first vaccine was created against
smallpox.
b. The first vaccine was created using the vaccinia virus.
c. The first vaccine was created against variola.
d. A & B
e. A, B & C - correct answer ✔✔E
Commensal species:
a. Typically do not cause harm to the host.
b. Likely become killed off from a round of antibiotics.
c. Can be present in many different parts of the body.
d. A & C
e. A, B & C - correct answer ✔✔E
Which Gram-positive pathogen would be expected to have teichoic acids present in their cell wall?
a. E. coli
d. HIV
b. Staphylococcus
e. Influenza
c. Salmonella - correct answer ✔✔B
4. When is the innate immune system activated?
a. Before the adaptive immune system is activated.
b. Before a pathogen has breached a physical barrier.
c. Only during a secondary immune response (i.e. not during a primary immune response)
d. A & B
,e. B & C - correct answer ✔✔A
5. Which of the following correctly describes inflammation?
a. Inflammation occurs when a pathogen gains entry through a surface wound.
b. Inflammation of the infected tissue typically only results in swelling.
c. Inflammation only results due to infections that are caused by pathogens.
d. Inflammation typically results in decreased vasodilation & decreased vascular permeability.
e. All of the above correctly describes inflammation. - correct answer ✔✔A
Vaccines are efficient in providing protective immunity against a specific pathogen, specifically by
stimulating the adaptive immune response in a manner that results in immunological memory.
a. True
b. False - correct answer ✔✔A
Clonal selection and clonal expansion are both observed in the innate immune response to an infection.
a. True
b. False - correct answer ✔✔B
Lymphocytes are unique in that they only function in adaptive immune responses.
a. True
b. False - correct answer ✔✔B
Which leukocyte, containing cytotoxic granules, would you expect to observe interacting with cells that
are infected with viral particles?
a. Neutrophils
c. Basophils
b. NK cells
d. Eosinophils - correct answer ✔✔B
,The most abundant leukocyte found in the blood are ______, whereas ______ are considered the least
abundant.
a. neutrophils ; lymphocytes
c. lymphocytes ; basophils
b. lymphocytes ; neutrophils
d. neutrophils ; basophils - correct answer ✔✔D
Which of the following immune cells are specialized to capture, engulf, and kill microorganisms? a.
Macrophage
d. A & B
b. Neutrophil
e. A, B & C
c. Monocytes - correct answer ✔✔E
Dendritic cells:
a. Present antigen to T cells to activate them.
b. Can be found in secondary lymphoid tissues.
c. Use only one type of receptor to recognize pathogens.
d. A & B e. A & C - correct answer ✔✔D
B lymphocytes and T lymphocytes both arise in the bone marrow and they both remain there to undergo
their maturation before migrating to organized secondary lymphoid tissues.
a. True
b. False - correct answer ✔✔B
Mast cells:
a. Release histamine and other active contents from their granules.
b. Kill other cells infected with certain viruses.
c. Arise from the myeloid progenitor.
d. A & C
, e. A, B & C - correct answer ✔✔D
Which of the following is true about T-cell receptors?
a. They are highly specific.
b. They are secreted after a T cell has been activated.
c. They are comprised of 4 chains.
d. They can be expressed as a soluble form.
e. All of the above are true. - correct answer ✔✔A
Which of the following pairs is matched incorrectly?
a. Antigen : foreign substance of many different types
b. BCRs : immunoglobulins
c. Helper T cell : kills pathogen-infected cells
d. Plasma cell : involved in antibody secretion
e. T-cell activation : cell division and differentiation are both observed - correct answer ✔✔C
All of the following are examples of secondary lymphoid tissues, except:
a. Bone marrow
d. Peyer's patches
b. Lymph nodes
e. A & B
c. Spleen - correct answer ✔✔A
Which of the following is true about a draining lymph node?
a. It is the site where mature lymphocytes can encounter pathogens.
b. They typically increase in size during an infection.
c. They can be referred to as "swollen gland."
d. It is the site where lymph-borne antigens are encountered by lymphocytes.
e. All of the above are true. - correct answer ✔✔E
