PCB 3233: Chapter 3 questions with complete solutions

PCB 3233: Chapter 3

C-reactive protein (CRP) and MBL level increase during ___________ - correct answer ✔✔Acute Phase
Response



CRP and MBL bind to what type of structures? - correct answer ✔✔Structures that are common in
pathogens but missing on human cells



CRP and MBL function - correct answer ✔✔Initiate complement activation



CRP specifically binds to - correct answer ✔✔phosphorylcholine components of LPS of bacterial and
fungal cell walls



Can CRP bind to phosphorylcholine in human cells? - correct answer ✔✔No



CRP subunits and family - correct answer ✔✔5 subunits and pentraxin family



CRP can activate which pathway? How? - correct answer ✔✔They can activate classical pathway by
binding with C1q in absence of antibodies



Is the cascade pathway activated by CRP any different? - correct answer ✔✔No



C1q is utilized only in ________________ pathway - correct answer ✔✔Classical



CRP binds to __________ of C1q - correct answer ✔✔Stalk



Antibodies bind to ____________ of C1q - correct answer ✔✔Globular heads



MBL binds to which types of pathogens? - correct answer ✔✔Bacteria and yeast