Pharmacokinetics and Pharmacodynamics Questions
with correct answers
Pharmacology Correct Answer-The study that deals with chemicals that
affect the body's functioning. (p.723)
Pharmacodynamics Correct Answer-The process by which drugs alter
cell physiology and affect the body. (p. 727)
Pharmacokinetics Correct Answer-The effect of the body on the drug.
The movement of drug molecules in the body in relation to the drug's
absorption, distribution, metabolism, and excretion. (p. 725)
Mechanisms of Drug Action (4 of them) Correct Answer-Absorption,
Distribution, Metabolism, and Excretion, are collectively known as the
4__________________.
Absorption Correct Answer-The process by which a drug is transferred
from its site of entry into the body to the bloodstream. (p. 725)
6 Factors that influence absorption Correct Answer-1. Route of
administration, 2. Lipid Solubility, 3. pH, 4. Blood flow, 5. Local
conditions at site of administration. 6. Drug dosage. (p. (726)
Loading dose Correct Answer-A larger than normal dose, usually given
when a patient is in acute distress and the therapeutic effect is desired as
quickly as possible. (p. 726)
, Maintenance dose Correct Answer-The usual dosage given over a long
period of time. (p. 727)
Distribution Correct Answer-The movement of drugs by the circulatory
system to the site of action (glossary, G-6)
Factors affecting Distribution (3 of them) Correct Answer-1. Blood flow
to the tissues, 2. Drug's ability to leave the bloodstream, 3. Drug's ability
to enter the cells. (p. 727)
Blood-brain barrier Correct Answer-A structure in the brain made up of
tightly packed capillary walls that supply blood to the brain. Protects
brain from toxins. (p. (727)
Metabolism (aka 'biotransformation') Correct Answer-The change of a
drug from its original form to a new form. The liver is the primary site
for this action. The drug is broken down into an inactive form. (p. 727)
Excretion (pharmacologic) Correct Answer-The process of the removal
of a drug and/or its metabolites from the body. (p. 727)
The major avenues of excretion of drugs Correct Answer-The kidneys,
the lungs, bile into the GI tract, sweat, salivary, mammary glands are all
avenues for this process. (p.727)
with correct answers
Pharmacology Correct Answer-The study that deals with chemicals that
affect the body's functioning. (p.723)
Pharmacodynamics Correct Answer-The process by which drugs alter
cell physiology and affect the body. (p. 727)
Pharmacokinetics Correct Answer-The effect of the body on the drug.
The movement of drug molecules in the body in relation to the drug's
absorption, distribution, metabolism, and excretion. (p. 725)
Mechanisms of Drug Action (4 of them) Correct Answer-Absorption,
Distribution, Metabolism, and Excretion, are collectively known as the
4__________________.
Absorption Correct Answer-The process by which a drug is transferred
from its site of entry into the body to the bloodstream. (p. 725)
6 Factors that influence absorption Correct Answer-1. Route of
administration, 2. Lipid Solubility, 3. pH, 4. Blood flow, 5. Local
conditions at site of administration. 6. Drug dosage. (p. (726)
Loading dose Correct Answer-A larger than normal dose, usually given
when a patient is in acute distress and the therapeutic effect is desired as
quickly as possible. (p. 726)
, Maintenance dose Correct Answer-The usual dosage given over a long
period of time. (p. 727)
Distribution Correct Answer-The movement of drugs by the circulatory
system to the site of action (glossary, G-6)
Factors affecting Distribution (3 of them) Correct Answer-1. Blood flow
to the tissues, 2. Drug's ability to leave the bloodstream, 3. Drug's ability
to enter the cells. (p. 727)
Blood-brain barrier Correct Answer-A structure in the brain made up of
tightly packed capillary walls that supply blood to the brain. Protects
brain from toxins. (p. (727)
Metabolism (aka 'biotransformation') Correct Answer-The change of a
drug from its original form to a new form. The liver is the primary site
for this action. The drug is broken down into an inactive form. (p. 727)
Excretion (pharmacologic) Correct Answer-The process of the removal
of a drug and/or its metabolites from the body. (p. 727)
The major avenues of excretion of drugs Correct Answer-The kidneys,
the lungs, bile into the GI tract, sweat, salivary, mammary glands are all
avenues for this process. (p.727)
