Pharmacodynamics Questions with correct answers
pharmacodynamics Correct Answer-the study of how drugs produce
their effects in the body
Pharmacodynamics of an administered drug includee: Correct Answer-
1) mechanism of action (how drug produces its pharmacologic effect)
2) pharmacological effect (anticipated results of the drugs)
Types of pharmacological effects Correct Answer-1) Therapeutic
2) Adverse effects
drug action level/general effect Correct Answer-usually occurs at the
cellular level within a target cell, tissue, or organ system
represents biochemical and/or physiologic changes that alter EXISTING
cell functions--do not create new cellular functinos
Mechanism of drug action: Physical and Chemical Mechanisms Correct
Answer-some drugs produce responses by physicall or chemically
altering the cell or its environment without interacting with cellular
receptors
Ex: general anesthetics, mineral oil facilitating passage of feces through
lower GI tract
, Drug Receptor Correct Answer-component of cell to which drug binds
and through which their chain of biochemical evens is initiated. MOST
DRUGS exerit their effect by activating such a receptor
generally the same receptor to which the body's own regulatory
molecules bind (hormones and neurotransmitters)
often proteins on or within cell
Drug effects at receptors Correct Answer-1) mimic the action of the
body's own regulatory molecules
2) black the action of the body's regulatory molecules
Signal transduction Correct Answer-(transmembrane signaling)
how external signals are transformed into intracellular messages that
control cell function--most signaling accomplished by only a few
molecular mechanisms
Four basic mechanisms of transmembrane signaling Correct Answer-1)
lipid-soluble ligand that crosses the membrane and acts on the
intracellular receptor
2) transmembrane receptor protein whose intracellular enzymatic
activity is regulated by a ligand that binds to a site on the protein's
extracellular domain
pharmacodynamics Correct Answer-the study of how drugs produce
their effects in the body
Pharmacodynamics of an administered drug includee: Correct Answer-
1) mechanism of action (how drug produces its pharmacologic effect)
2) pharmacological effect (anticipated results of the drugs)
Types of pharmacological effects Correct Answer-1) Therapeutic
2) Adverse effects
drug action level/general effect Correct Answer-usually occurs at the
cellular level within a target cell, tissue, or organ system
represents biochemical and/or physiologic changes that alter EXISTING
cell functions--do not create new cellular functinos
Mechanism of drug action: Physical and Chemical Mechanisms Correct
Answer-some drugs produce responses by physicall or chemically
altering the cell or its environment without interacting with cellular
receptors
Ex: general anesthetics, mineral oil facilitating passage of feces through
lower GI tract
, Drug Receptor Correct Answer-component of cell to which drug binds
and through which their chain of biochemical evens is initiated. MOST
DRUGS exerit their effect by activating such a receptor
generally the same receptor to which the body's own regulatory
molecules bind (hormones and neurotransmitters)
often proteins on or within cell
Drug effects at receptors Correct Answer-1) mimic the action of the
body's own regulatory molecules
2) black the action of the body's regulatory molecules
Signal transduction Correct Answer-(transmembrane signaling)
how external signals are transformed into intracellular messages that
control cell function--most signaling accomplished by only a few
molecular mechanisms
Four basic mechanisms of transmembrane signaling Correct Answer-1)
lipid-soluble ligand that crosses the membrane and acts on the
intracellular receptor
2) transmembrane receptor protein whose intracellular enzymatic
activity is regulated by a ligand that binds to a site on the protein's
extracellular domain
