Fundamentals of Glomerulonephritis Practice Solution Manual Already Passed

Fundamentals of Glomerulonephritis Practice Solution Manual Already Passed what is glomerulonephropathy? - Answers glomerulonephritis features of nephritic syndrome? - Answers hematuria proteinuria hypertension azotemia features of nephrotic syndrome? - Answers huge proteinuria (3.5g/day) hypoalbuminaemia oedema lipiduria hyperlipidaemia (no hematuria or impairment of renal function) who is minimal change disease very common in? - Answers children what type of glomerular disease causes nephritic syndrome? - Answers proliferative glomerular disease what type of glomerular disease causes nephrotic syndrome? - Answers non-proliferative glomerular disease poisons drugs infections tumours that cause minimal change disease? - Answers mecury and lead nsaid hiv, mononucleosis hodgkins is renal function normal in minimal change disease? - Answers yes what happens to the GBM eventually in minimal change disease? - Answers loss of negative pressure due to loss of epitheial foot processes Is focal segmental glomerulosclerosis nephrotic or nephritic syndrome? - Answers nephrotic features of focal segmental glomerulosclerosis? - Answers non selective proteinuria thickened BM loss of foot processes what is deposited in Focal segmental glomerularsclerosis? - Answers IgM or C3 is membranous glomerularnephropathy nephrotic or nephritic? - Answers nephrotic, main NS in adults is membranous GN usually primary or secondary? what are the secondary causes? - Answers usually primary SLE, Hep B, Malignancy, Drugs which nephrotic syndrome is immune mediated? - Answers Membranous GN (GP330 Antibody) what immune complex is deposited in Membranous GN? - Answers IgG along capillary walls What GN is Kimmelsteil-Wilson Lesion indicative of and what is it? - Answers diabetic nephropathy nodular expansion of mesangium in which GN is a lot of hyaline deposited and albumin involved? - Answers diabetic nephropathy the two types of amyloid and conditions that cause its deposition? - Answers Light chain '(AL) - myeloma, MGUS, Waldenstroms Inflammatory (AA) - rheum arthritis, osteoporosis, tb, what caan amyloid deposits in the glomerulus look like? (condition) - Answers diabetic nephropathy what is congo red stain used to identify? - Answers amyloid whta is oliguria? - Answers low urine output Who does post infectious GN usually occur in? - Answers children after strep throat or impetigo what are features of acute post infection GN? - Answers cola urine 10-14 days post urine edema/hypertension rbc casts decreased complement levels increased mesengial cells what is deposited in post infectious GN? - Answers IgG and C3 what does post infectious GN appear like? - Answers hump or flame like deposits neutrophil infiltration What is the most common nephropathy worldwide? - Answers IgA nephropathy (only 30% of this is progressive) IgA nephropathy associations? - Answers HIV Liver disease IBD Psoriasis when will immunosuppression be used in IgA nephropathy? - Answers if crescents seen on biopsy where are immune complexes deposited in IgA nephropathy? - Answers around the mesengial cells which GN can present as nephritic or nephrotic? - Answers membranoproliferative GN what is a very common feature of Membranoproliferative GN? - Answers Low C3 Name the 3 types of Membranoproliferative GN? - Answers Type 1- Mesangiocapillary GN Type 2 =- Dense Deposit Disease (linear not granular deposits) Type 3 = type 1 plus membranous pattern what GN shows double contours on silver stain? - Answers type 1 Membranoproliferative GN what are deposited in Membranoproliferative GN? - Answers IgG C3 which type of Membranoproliferative GN has a 100% recurrence rate on transplant? - Answers type 2 dense deposit disease Name the 3 types of Rapidly progressive glomerulonephritis? - Answers Type 1 - anti