NSG 6005 Pharm Midterm Questions With
Solutions
A patient's nutritional intake and lab work reflect hypoalbuminemia. This is critical to
prescribing because: Distribution of drugs to target tissue may be affected
Drugs that have a significant first-pass effect: Are rapidly metabolized by the liver and
may have little if any desired action
The route of excretion of a volatile drug will be: The lungs
The point in time on the drug concentration curve that indicated the first sign of a therapeutic
effect is the: Onset of action
Factors that affect gastric drug absorption include: Lipid solubility of the drug
Which one of the following statements about bio availability is true? Bio availability
issues are especially important for drugs with narrow therapeutic ranges or sustained release
mechanisms.
, NSG 6005 Pharm Midterm Questions With
Solutions
Steady State is: When the amount of drug in the body remains constant.
The time required for the amount of drug in the body to decrease by 50% is called: Half-
life
An advantage of prescribing a sublingual medication is that the medication is: Absorbed
rapidly
Drugs that use CYP 3A4 isoenzymes for metabolism may:
1. Induce the metabolism of another drug
2. Inhibit the metabolism of another drug
3. Both 1 and 2
4. Neither 1 nor 2 BOTH A and B
Induce the metabolism of another drug
Solutions
A patient's nutritional intake and lab work reflect hypoalbuminemia. This is critical to
prescribing because: Distribution of drugs to target tissue may be affected
Drugs that have a significant first-pass effect: Are rapidly metabolized by the liver and
may have little if any desired action
The route of excretion of a volatile drug will be: The lungs
The point in time on the drug concentration curve that indicated the first sign of a therapeutic
effect is the: Onset of action
Factors that affect gastric drug absorption include: Lipid solubility of the drug
Which one of the following statements about bio availability is true? Bio availability
issues are especially important for drugs with narrow therapeutic ranges or sustained release
mechanisms.
, NSG 6005 Pharm Midterm Questions With
Solutions
Steady State is: When the amount of drug in the body remains constant.
The time required for the amount of drug in the body to decrease by 50% is called: Half-
life
An advantage of prescribing a sublingual medication is that the medication is: Absorbed
rapidly
Drugs that use CYP 3A4 isoenzymes for metabolism may:
1. Induce the metabolism of another drug
2. Inhibit the metabolism of another drug
3. Both 1 and 2
4. Neither 1 nor 2 BOTH A and B
Induce the metabolism of another drug
