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CCRN- Endocrine Concepts (Barron's) Questions and Correct Answers | Latest Update

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measure of the number of particles in a solution; expressed as milliosmoles -:- serum osmolality (osmolality of body fluids) what is the normal osmolality of body fluids? -:- 275-295 mOsm/kg (hypo-osmolar 275 hyper-osmolar 295) true or false: cell membranes are permeable to water, therefore serum osmo will affect the intracellular fluid (ICF) osmo -:- true note that serum sodium, BUN, and glucose each play a role in the calculation of serum osmolality. 2 | P a g e | G r a d e A + | 2 0 2 4 / 2 0 2 5 Excel! 2 0 2 4 /2025 | © copyright | This work may not be copied for profit gain 2(Na+) + BUN/5 + glucose/20 = 275-295 mOsm/kg. According to the formula above, an increase in serum sodium, BUN, and/or glucose will affect the serum osmo, increasing or decreasing the serum osmolality? -:- increase where is the hypothalamus located? -:- pituitary gland the endocrine "monitoring central" and regulates temperature, intake drives, autonomic nervous system (sympathetic/parasympathetic) -:- hypothalamus what two parts of the body release hormones that are NOT controlled by the hypothalamus? -:- 1) pancreas 2) parathyroid what are three things that the hypothalamus regulates? 3 | P a g e | G r a d e A + | 2 0 2 4 / 2 0 2 5 Excel! 2 0 2 4 /2025 | © copyright | This work may not be copied for profit gain -:- 1) temperature 2) intake drives 3) autonomic nervous system (sympathetic/parasympathetic) where is ADH formed? -:- hypothalamus where is ADH stored? -:- posterior pituitary this works on the distal convoluted and collecting tubule of kidney to REABSORB WATER (prevents diuresis) and concentrates urine (normal urine osmolality (1.010-1.020) -:- ADH what is the pathophysiology of SIADH? (figure 10-1 pg 204) -:- too much ADH-- water retention-- decrease in serum Na+ (dilutional hyponatremia-CARDINAL SIGN); decreased urinary output; decreased osmolality (hypo-osmolality) 4 | P a g e | G r a d e A + | 2 0 2 4 / 2 0 2 5 Excel! 2 0 2 4 /2025 | © copyright | This work may not be copied for profit gain what are 5 etiologies of SIADH? -:- 1) oat cell carcinoma (most common) 2) viral pneumonia (most common) 3) head problems (most common) 4) increased osmolality, anesthesia, analgesia, stress 5) thiazide diuretics (esp elderly

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2024 /2025 | © copyright | This work may not be copied for profit gain Excel!




CCRN- Endocrine Concepts (Barron's)
Questions and Correct Answers | Latest
Update
measure of the number of particles in a solution; expressed as milliosmoles


✓ -:- serum osmolality (osmolality of body fluids)




what is the normal osmolality of body fluids?


✓ -:- 275-295 mOsm/kg

✓ (hypo-osmolar <275

✓ hyper-osmolar >295)




true or false:


cell membranes are permeable to water, therefore serum osmo will affect the intracellular

fluid (ICF) osmo


✓ -:- true




note that serum sodium, BUN, and glucose each play a role in the calculation of serum

osmolality.




1|P a g e | G r a d e A + | 2 0 2 0 2 5

,2024 /2025 | © copyright | This work may not be copied for profit gain Excel!



2(Na+) + BUN/5 + glucose/20 = 275-295 mOsm/kg. According to the formula above, an

increase in serum sodium, BUN, and/or glucose will affect the serum osmo, increasing or

decreasing the serum osmolality?


✓ -:- increase




where is the hypothalamus located?


✓ -:- pituitary gland




the endocrine "monitoring central" and regulates temperature, intake drives, autonomic

nervous system (sympathetic/parasympathetic)


✓ -:- hypothalamus




what two parts of the body release hormones that are NOT controlled by the

hypothalamus?


✓ -:- 1) pancreas

2) parathyroid




what are three things that the hypothalamus regulates?



2|P a g e | G r a d e A + | 2 0 2 0 2 5

, 2024 /2025 | © copyright | This work may not be copied for profit gain Excel!



✓ -:- 1) temperature

2) intake drives


3) autonomic nervous system (sympathetic/parasympathetic)




where is ADH formed?


✓ -:- hypothalamus




where is ADH stored?


✓ -:- posterior pituitary




this works on the distal convoluted and collecting tubule of kidney to REABSORB WATER

(prevents diuresis) and concentrates urine (normal urine osmolality (1.010-1.020)


✓ -:- ADH




what is the pathophysiology of SIADH? (figure 10-1 pg 204)


✓ -:- too much ADH--> water retention--> decrease in serum Na+

(dilutional hyponatremia-CARDINAL SIGN); decreased urinary output;

decreased osmolality (hypo-osmolality)


3|P a g e | G r a d e A + | 2 0 2 0 2 5

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