Assessment Study Guide Questions with
verified Marking Scheme latest version
2024/2025
A patient with a known history of abdominal wall desmoid tumors
should be screened for
a.) Lung cancer
b.) Colon polyps
c.) Breast cancers
d.) Medullary thyroid cancer
e.) Pancreatic cancer - correct answer (b)
Gardener's syndrome is colon polyps with desmoid tumors. The
gene responsible is APC and is inherited in a autosomal dominant
pattern
Which chemotherapy agent causes neutropenic enterocolitis
a.) Vincristine
b.) Cisplatin
c.) Cyclophosphamide
d.) 5-FU
e.) Cytarabine - correct answer (e)
Cytarabine
,Which chemotherapy agent causes severe peripheral
neuropathy?
a.) Vincristine
b.) Methotrexate
c.) Tamoxifen
d.) 5-FU
e.) Cisplatin - correct answer (e)
A 43yr old presents with weight loss & watery diarrhea.
Investigation reveals hypokalemia with a pancreatic mass. Which
of the following would support the diagnosis of a VIPoma?
a.) Achlorhydria
b.) Hypoglycaemia
c.) Increased Pancreatic polypeptide
d.) Migratory erythema
e.) Pellagra - correct answer (a)
1.) Watery diarrhea 2.) ↓Cl 3.) Acidosis 4.) ↓K
Which of the following does NOT form part of the
somatostatinoma syndrome?
a.) Hypoglycemia
b.) Gallbladder disease
c.) Diarrhea
d.) Steatorrhea
,e.) None of the above - correct answer (a)
1) Diabetes 2) Diarrhea 3) Gallstones
An inhibitor of platelet aggregation is
a.) Prostacyclin I
b.) Thromboxane A2
c.) Adenosine Diphosphate
d.) Serotonin
e.) vWF - correct answer (a)
It counters the action of Thromboxane A2 which is a potent
vasoconstrictor and platelet aggregator
PGI (prostacyclin): platelet inhibition, vasodilation and
bronchodilation
The most common cause of GI bleeding in children is
a.) Meckels diverticulum
b.) Anal fissure
c.) Intussusception
d.) Upper GI bleed - correct answer (b)
Anal fissure
(Note: the most common MASSIVE GI bleeding is from Meckels)
, Which motility prokinetic drug and its mechanism of action is
correct?
a.) Cisapride -- Anticholinergic
b.) Erythromycin -- Motilin receptor agonist
c.) Metoclopramide -- Serotonin agonist
d.) Domperidone -- Serotonin agonist
e.) All are correct - correct answer (b)
Metoclopramide/Domperidone have unknown mechanisms of
action. Cisapride is a serotonin agonist.
A 60yr old patient presents with vague abdominal pain, weight
loss, recent onset diabetes, and a patchy erythematous rash in
the pelvic region as well as around the mouth and anus. The
most likely diagnosis is?
a.) VIPoma
b.) Syphilis
c.) Glucagonoma
d.) Gastrinoma
e.) Insulinoma - correct answer (c)
Patients with glucagonoma usually have mild diabetes and a
severe dermatitis (necrolytic migratory erythema). These
patients may also demonstrate malnutrition, anemia, glossitis,
and venous thrombosis. The majority of patients have metastatic
disease at the time of diagnosis.