Nursing Care, 11th Edition by Jacqueline Burchum,
Laura Rosenthal Chapter 1-
drug - ANSWER A chemical that can affect the living process
Pharmacology - ANSWER The study of drugs and their interactions with living
systems
Clinical Pharmacology - ANSWER The study of drugs in humans
Therapeutics - ANSWER AKA "Pharmacotherapeutics"; The use of drugs to
diagnose, prevent or treat disease or to prevent pregnancy
The BIG Three Characteristics any drug can have - ANSWER 1) Effectiveness
2) Safety
3) Selectivity
Effectiveness - ANSWER Effective Drug= One that elicits responses for which it's
given
*Most important property for a drug to have
Safety - ANSWER Safe Drug= One that can't produce harmful effects even
administered in very high doses for a long time.
*All drugs have the ability to cause injury, especially with high doses and prolonged
use
Selectivity - ANSWER Selective Drug= one that elicits only the response for which
it's given
There's no such thing as a wholly selective drug because all drugs cause side effects
Additional Properties of an 'Ideal Drug' - ANSWER 1) Reversible Action
2) Predictability
3) Ease of Administration
4) Freedom from Drug Interactions
5) Low Cost
6) Chemical Stability
7) Possession of Simple Generic Names
Factors that Determine the Intensity of Drug Responses - ANSWER
ADMINISTRATION
-Med Errors
- Patient Adherence
PHARMACOKINETICS
, - Absorption
- Distribution
- Metabolism
- Excretion
*SOURCES OF INDIVIDUAL VARIATION
-Physiologic Variables
-Pathologic Variables
-Genetic Variables
PHARMACODYNAMICS
- Drug-receptor interactions
-Patients functional state
-Placebo effect
Pharmacokinetics - ANSWER The impact of the BODY on the drugs
Four Processes
1) Drug Absorption
2) Drug Distribution
3) Drug Metabolism
4) Drug Excretion
Pharmacodynamics - ANSWER The impact of DRUGS on the body
Examples
- Drug-receptor interactions
- Patients functional state
- Placebo effect
Sources of Variation - ANSWER Physiologic Variables
- age, weight, gender
Pathologic Variables
-diminished function in kidney or liver, major organs of elimination
Genetic Variables
Nurses Responsibility Regarding Medications - ANSWER 5 Rights And other rights
5 Rights of Drug Administration - ANSWER 1) Right DRUG
2) Right PATIENT
3) Right DOSE
4) Right ROUTE
5) Right TIME
Other Rights if Drug Administration - ANSWER - Right Assessment
- Right Documentation
- Right Evaluation
- Patient's Right to Education
- Patient's Right to Refusal