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Practice Test 1 CCRN (Pass CCRN) Updated 2024/2025 Verified 100%

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What is the difference between an anaphylactic and anaphylactoid reaction? - Anaphylactoid reaction is clinically indistinguishable from anaphylactic reaction but does not require previous exposure to the antigen. Anaphylactoid reaction is not IgE mediated, and direct activation and degranulation of mast cells are thought to be triggered by the complement system. Anaphylactic reaction requires previous exposure to the antigen and is IgE mediated What happens to SvO2 if oxygen delivery decreases for any reason - SvO2 is a reflection of oxygen reserve. If oxygen delivery is decreased, oxygen consumption continues, and oxygen reserve decreases. SvO2 decreases any time the delivery of oxygen decreases or the consumption of the tissues increases What ventilator parameter indicates fluid volume excess? - An A:a gradient greater than 10 mm Hg is a reflection of a diffusion defect. Note that the process of diffusion is between A (alveolus) and (a) arterial blood. An increase in intraalveolar fluid dilutes and inactivates surfactant, causing alveolar collapse (decreasing vital capacity) and decreases lung compliance. Peak inspiratory pressure increases reflect a decrease in lung compliance What antihypertensive meds work best in African american patients? - African-Americans do not respond well to angiotensin-converting enzyme inhibitors (e.g., captopril [Capoten]), but they do respond well to an angiotensin II blocker (valsartan [Diovan]). Of the beta-blockers, labetalol works best. Of the calcium channel blockers, diltiazem works best How can you differentiate the cause of jaundice? - An increase in direct bilirubin is associated with biliary obstruction because direct bilirubin is conjugated. An increase in indirect bilirubin is associated with hepatic disease or excessive hemolysis because indirect bilirubin is unconjugated What is vasogenic cerebral edema? - Vasogenic cerebral edema is an increase in extracellular fluid caused by a breakdown of the blood-brain barrier with the resultant increase in vascular permeability. This cerebral edema begins locally and becomes more generalized. Common causes are trauma (including surgical trauma), tumors, hemorrhage, and abscesses What does autonomy refer to? - The patient's right to make decisions for themselvesWhat does beneficence mean? - Obligation to do good What does nonmaleficence mean? - Obligation to do no harm What does fidelity mean? - the obligation to abide by agreements and responsibilities What does veracity mean? - The obligation to tell the truth What are Diagnosis-Related groups? - DRGs constitute a prospective payment program for Medicare patients. Payment is based on primary and secondary diagnosis, primary and secondary procedures, age, and length of hospitalization BNP is secreted in response to? - Ventricular wall stretch What are omnious signs in a patient with status asthmaticus? - A normalization or increase in the PaCO2. This patient is still tachypneic, and if ventilation is normal, PaCO2 should be decreased. The other ominous sign in this patient would be absence of wheezing or rhonchi, because they would indicate that ventilation is insufficient to cause these noises. What problems arise from losses from the GI tract? - Any loss results in hypokalemia. Vomiting results in loss of acidic contents, whereas losses below the pylorus result is alkalitic losses leading to metabolic acidosis. Fluid is sequestered in the intestine leading to hypovolemia, which could cause hypovolemic shock. Actual problems are worse than potential problems!! - What lab values define acute respiratory failure? - 50-50! PaO2<50 and/or PaCO2>50Hyperkalemia can cause what? - Diarrhea-increases gastric motility Flaccid paralysis- partially depolarizes muscle cells, prevents further depolarization Every 1 inch increase in abdominal girth equates to how much blood accumulation in the abdomen - 500-1000mL What pacing method would be used in a patient in atrial fib? - VVI- you don't want to sense or pace the atria. 1st letter-paced chamber 2nd letter-chamber sensed Mitral stenosis is associated with what? - Pinkish discoloration of the cheeks. It is a diastolic murmur What murmur is associated with widened pulse pressure? - Aortic regurg What murmur is associated with narrowed pulse pressure? - Mitral regurg What lead changes are associated with left ventricle hyperthrophy? - Strain pattern in V5 and V6 (asymmetric T wave inversion) When the depth of the S wave in lead V1 or V2 plus the height of the R wave in lead V5 or V6 is 35 mm or greater, this constitutes voltage What lead changes are associated with right ventricle hypertrophy? - strain pattern in V1 and V2. Prominent R wave in V1 reverse progression of the R wave across the precordium. What organ system is the most common to fail in severe sepsis? - Hematologic- coagulopathies are common in severe sepsisWhat are the early signs of hypoglycemia? - The early signs of hypoglycemia are mediated by the sympathetic nervous system, which acts to mobilize glucose stores (tachycardia, tachypnea, diaphoresis). Later signs of hypoglycemia are related to low glucose levels in the brain (neuroglycopenia) **Early signs can be masked in pts taking beta-blockers A simple way to estimate CVP is to add 5 cm to the measured height that the jugular veins are distended above the sternal angle (angle of Louis) with the patient in a 45-degree angle - What is the most common cause of right ventricular failure? - Left ventricular failure- causes pulmonary congestion and pulmonary HTN which increases the workload for the right side of the heart Other causes- primary pulmonary hypertension, RV infarction, pulmonic stenosis, PE, mitral stenosis

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Practice Test 1 CCRN (Pass CCRN)
What is the difference between an anaphylactic and anaphylactoid reaction? - Anaphylactoid
reaction is clinically indistinguishable from anaphylactic reaction but does not require previous exposure
to the antigen. Anaphylactoid reaction is not IgE mediated, and direct activation and degranulation of
mast cells are thought to be triggered by the complement system. Anaphylactic reaction requires
previous exposure to the antigen and is IgE mediated



What happens to SvO2 if oxygen delivery decreases for any reason - SvO2 is a reflection of oxygen
reserve. If oxygen delivery is decreased, oxygen consumption continues, and oxygen reserve decreases.
SvO2 decreases any time the delivery of oxygen decreases or the consumption of the tissues increases



What ventilator parameter indicates fluid volume excess? - An A:a gradient greater than 10 mm
Hg is a reflection of a diffusion defect. Note that the process of diffusion is between A (alveolus) and (a)
arterial blood. An increase in intraalveolar fluid dilutes and inactivates surfactant, causing alveolar
collapse (decreasing vital capacity) and decreases lung compliance. Peak inspiratory pressure increases
reflect a decrease in lung compliance



What antihypertensive meds work best in African american patients? - African-Americans do not
respond well to angiotensin-converting enzyme inhibitors (e.g., captopril [Capoten]), but they do
respond well to an angiotensin II blocker (valsartan [Diovan]). Of the beta-blockers, labetalol works best.
Of the calcium channel blockers, diltiazem works best



How can you differentiate the cause of jaundice? - An increase in direct bilirubin is associated with
biliary obstruction because direct bilirubin is conjugated. An increase in indirect bilirubin is associated
with hepatic disease or excessive hemolysis because indirect bilirubin is unconjugated



What is vasogenic cerebral edema? - Vasogenic cerebral edema is an increase in extracellular fluid
caused by a breakdown of the blood-brain barrier with the resultant increase in vascular permeability.
This cerebral edema begins locally and becomes more generalized. Common causes are trauma
(including surgical trauma), tumors, hemorrhage, and abscesses




What does autonomy refer to? - The patient's right to make decisions for themselves

, What does beneficence mean? - Obligation to do good



What does nonmaleficence mean? - Obligation to do no harm



What does fidelity mean? - the obligation to abide by agreements and responsibilities



What does veracity mean? - The obligation to tell the truth



What are Diagnosis-Related groups? - DRGs constitute a prospective payment program for
Medicare patients. Payment is based on primary and secondary diagnosis, primary and secondary
procedures, age, and length of hospitalization



BNP is secreted in response to? - Ventricular wall stretch



What are omnious signs in a patient with status asthmaticus? - A normalization or increase in the
PaCO2. This patient is still tachypneic, and if ventilation is normal, PaCO2 should be decreased. The other
ominous sign in this patient would be absence of wheezing or rhonchi, because they would indicate that
ventilation is insufficient to cause these noises.



What problems arise from losses from the GI tract? - Any loss results in hypokalemia. Vomiting
results in loss of acidic contents, whereas losses below the pylorus result is alkalitic losses leading to
metabolic acidosis. Fluid is sequestered in the intestine leading to hypovolemia, which could cause
hypovolemic shock.



Actual problems are worse than potential problems!! -




What lab values define acute respiratory failure? - 50-50!

PaO2<50 and/or PaCO2>50

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