ASCP MLT TEST QUESTIONS WITH
CORRECT ANSWERS
Which of the following is true about Bence-Jones protein when performing the heat
precipitation test? - Answer-Precipitates between 40° and 60°C but redissolves at
100°C
Which of the following immunoglobulin classes is chiefly responsible for the
degranulation of mast cells and basophils: - Answer-IgE
When is a trough blood sample for therapeutic drug monitoring usually obtained? -
Answer-Just before the next scheduled dose
Which of the following is true of genotype screening in pharmacogenomics? - Answer-
Genotyping does not take into account drug interactions which can affect metabolism.
A test for microalbuminuria is used most often to monitor patients with which of the
following diseases or conditions? - Answer-Diabetes
The cytospin technique perfectly preserves the morphology of blood cells in a fluid
sample. - Answer-false
Which chromosome demonstrates a partial or full gene loci deletion in various forms of
beta thalassemia? - Answer-Chromosome 11
Match the names of the PCR stages to their definitions. - Answer-The DNA is heated to
break the hydrogen bonds resulting in single stranded DNA. Denaturation
The DNA primers attach to the DNA strands. Annealing
The DNA polymerase synthesize new strands of DNA. Extension
Patient 1234 has a positive antinuclear antibody (ANA) test with a centromere pattern at
a 1:1280 titer. - Answer-You point out that centromere antibodies have been known to
occur years prior to the onset of the disease and the patient should be carefully
examined and monitored for the development of other symptoms.
What is the antigen carried by most strains of Streptococcus anginosus (milleri)? -
Answer-f
Which method is employed if the following procedural steps were used to identify M.
kansasii?
, 1 - Extraction
2 - Denaturization
3 - Hybridization
4 - Hydrolysis of excess reagent
5 - Detection of acridinium ester - Answer-Nucleic acid probes
HLA-A and HLA-B antigens can be detected using which of the following techniques? -
Answer-Lymphocyte cytotoxicity
What is the normal cellularity of an iliac crest bone marrow biopsy in a 50 year old male:
- Answer-50%
Which one of the following statements about acetaminophen metabolism is false? -
Answer-It is metabolized in the kidney
Match these autoimmune diseases with their corresponding serological markers: -
Answer-Primary biliary cirrhosis Antimitochondrial antibodies
CREST syndrome Anticentromere antibodies
Wegener's granulomatosis Antineutrophilic antibodies
Rheumatic fever Antimyocardial antibodies
Which of the following factors would not affect an orally-administered drug's absorption
and/or distribution in the body? - Answer-The position of the patient when the drug is
taken (sitting vs. standing)
The clinical Gram stain taken from an endocervix revealed many WBC's with both
intracellular and extracellular gram- negative diplococci. The specimen was plated onto
a Modified Thayer-Martin plate and incubated. Following incubation, colonies
resembling N. gonorrheae were inoculated into separate CTA tubes containing glucose,
lactose, sucrose and maltose. The fluorescent monoclonal antibody test was positive as
well as the CTA maltose and glucose tubes. What is the most appropriate next step? -
Answer-Analyze another maltose tube using a known strain of N. gonorrhoeae
Cell size is indicated by forward scatter and granularity is indicated by side scatter in
flow cytometry. - Answer-TRUE
A track star was in the locker room after a competition when one of his teammates
noticed light brown circular lesions on his upper back. The agent MOST likely
responsible for this condition is: - Answer-Malassezia furfur
Which of the following organisms has been known to cause epidemic tinea capitis in
children but almost never affects adults? - Answer-Microsporum audouinii
It is OK to change a physician's orders without calling the office first when: - Answer-It is
never acceptable to change a physician's order without calling the office or department
first. All changes must have approval beforehand.
CORRECT ANSWERS
Which of the following is true about Bence-Jones protein when performing the heat
precipitation test? - Answer-Precipitates between 40° and 60°C but redissolves at
100°C
Which of the following immunoglobulin classes is chiefly responsible for the
degranulation of mast cells and basophils: - Answer-IgE
When is a trough blood sample for therapeutic drug monitoring usually obtained? -
Answer-Just before the next scheduled dose
Which of the following is true of genotype screening in pharmacogenomics? - Answer-
Genotyping does not take into account drug interactions which can affect metabolism.
A test for microalbuminuria is used most often to monitor patients with which of the
following diseases or conditions? - Answer-Diabetes
The cytospin technique perfectly preserves the morphology of blood cells in a fluid
sample. - Answer-false
Which chromosome demonstrates a partial or full gene loci deletion in various forms of
beta thalassemia? - Answer-Chromosome 11
Match the names of the PCR stages to their definitions. - Answer-The DNA is heated to
break the hydrogen bonds resulting in single stranded DNA. Denaturation
The DNA primers attach to the DNA strands. Annealing
The DNA polymerase synthesize new strands of DNA. Extension
Patient 1234 has a positive antinuclear antibody (ANA) test with a centromere pattern at
a 1:1280 titer. - Answer-You point out that centromere antibodies have been known to
occur years prior to the onset of the disease and the patient should be carefully
examined and monitored for the development of other symptoms.
What is the antigen carried by most strains of Streptococcus anginosus (milleri)? -
Answer-f
Which method is employed if the following procedural steps were used to identify M.
kansasii?
, 1 - Extraction
2 - Denaturization
3 - Hybridization
4 - Hydrolysis of excess reagent
5 - Detection of acridinium ester - Answer-Nucleic acid probes
HLA-A and HLA-B antigens can be detected using which of the following techniques? -
Answer-Lymphocyte cytotoxicity
What is the normal cellularity of an iliac crest bone marrow biopsy in a 50 year old male:
- Answer-50%
Which one of the following statements about acetaminophen metabolism is false? -
Answer-It is metabolized in the kidney
Match these autoimmune diseases with their corresponding serological markers: -
Answer-Primary biliary cirrhosis Antimitochondrial antibodies
CREST syndrome Anticentromere antibodies
Wegener's granulomatosis Antineutrophilic antibodies
Rheumatic fever Antimyocardial antibodies
Which of the following factors would not affect an orally-administered drug's absorption
and/or distribution in the body? - Answer-The position of the patient when the drug is
taken (sitting vs. standing)
The clinical Gram stain taken from an endocervix revealed many WBC's with both
intracellular and extracellular gram- negative diplococci. The specimen was plated onto
a Modified Thayer-Martin plate and incubated. Following incubation, colonies
resembling N. gonorrheae were inoculated into separate CTA tubes containing glucose,
lactose, sucrose and maltose. The fluorescent monoclonal antibody test was positive as
well as the CTA maltose and glucose tubes. What is the most appropriate next step? -
Answer-Analyze another maltose tube using a known strain of N. gonorrhoeae
Cell size is indicated by forward scatter and granularity is indicated by side scatter in
flow cytometry. - Answer-TRUE
A track star was in the locker room after a competition when one of his teammates
noticed light brown circular lesions on his upper back. The agent MOST likely
responsible for this condition is: - Answer-Malassezia furfur
Which of the following organisms has been known to cause epidemic tinea capitis in
children but almost never affects adults? - Answer-Microsporum audouinii
It is OK to change a physician's orders without calling the office first when: - Answer-It is
never acceptable to change a physician's order without calling the office or department
first. All changes must have approval beforehand.
