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UVIC Biol 432 Molecular Endocrinology Midterm Random Questions with Correct Answers

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What vessel attaches the hypothalamus to the anterior pituitary? Correct Answer Portal hypophyseal vessel What type of receptor is the receptor for gonadotropin-releasing hormone (GnRH)? Correct Answer GPCR Gonadotropin-releasing hormone causes gonadotroph cells in the anterior pituitary to produce what two hormones? Correct Answer Luteinizing hormone and follicle stimulating hormone Luteinizing hormone and follicle stimulating hormone cause the testes to produce what sex hormone? What two hormones are produced by the ovaries when stimulated with LH and FSH? Correct Answer Testes: testosterone Ovaries: estrogen and progesterone What type of receptor is the receptor for corticotropin-releasing hormone? Correct Answer GPCR Corticotropin-releasing hormone is secreted by the hypothalamus in response to what? Correct Answer Stress In the anterior pituitary, pro-opiomelanocortin (POMC) is modified into what? Correct Answer adrenocorticotropic hormone In the intermediate pituitary, hypothalamus, and skin, pro-opiomelanocortin (POMC) is modified into what? Correct Answer melanocyte stimulating hormone What is the enzyme involved in cleaving pro-opiomelanocortin? Correct Answer My main dude --> prohormone convertase Prohormone convertases (PC1 and PC2) cleave at what type of sites? Correct Answer Dibasic amino acid sites (Arg-Arg, Lys-Lys, Arg-Lys) [remember your biochemistry fam] In fish, frogs, octopus, etc. melanocyte stimulating hormone stimulates these pigment cells that permit colour change. Correct Answer Melanophores Melanin can absorb UV radiation and transform it into harmless heat, making it an excellent ___________. Correct Answer Photoprotectant

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UVIC Biol 432 Molecular Endocrinology
Midterm Random Questions with Correct
Answers
What vessel attaches the hypothalamus to the anterior pituitary? Correct Answer Portal
hypophyseal vessel

What type of receptor is the receptor for gonadotropin-releasing hormone (GnRH)?
Correct Answer GPCR

Gonadotropin-releasing hormone causes gonadotroph cells in the anterior pituitary to
produce what two hormones? Correct Answer Luteinizing hormone and follicle
stimulating hormone

Luteinizing hormone and follicle stimulating hormone cause the testes to produce what
sex hormone? What two hormones are produced by the ovaries when stimulated with
LH and FSH? Correct Answer Testes: testosterone
Ovaries: estrogen and progesterone

What type of receptor is the receptor for corticotropin-releasing hormone? Correct
Answer GPCR

Corticotropin-releasing hormone is secreted by the hypothalamus in response to what?
Correct Answer Stress

In the anterior pituitary, pro-opiomelanocortin (POMC) is modified into what? Correct
Answer adrenocorticotropic hormone

In the intermediate pituitary, hypothalamus, and skin, pro-opiomelanocortin (POMC) is
modified into what? Correct Answer melanocyte stimulating hormone

What is the enzyme involved in cleaving pro-opiomelanocortin? Correct Answer My
main dude --> prohormone convertase

Prohormone convertases (PC1 and PC2) cleave at what type of sites? Correct Answer
Dibasic amino acid sites (Arg-Arg, Lys-Lys, Arg-Lys) [remember your biochemistry fam]

In fish, frogs, octopus, etc. melanocyte stimulating hormone stimulates these pigment
cells that permit colour change. Correct Answer Melanophores

Melanin can absorb UV radiation and transform it into harmless heat, making it an
excellent ___________. Correct Answer Photoprotectant

, In the hypothalamus, alpha-melanocyte stimulating hormone plays a role in what?
Correct Answer Appetite regulation and suppression

What type of ACTH regulator is Vasopressin? Correct Answer Positive regulator since it
works synergistically with corticotropin-releasing hormone.

What type of ACTH regulator is Oxytocin? Correct Answer Negative regulator [maybe
try oxytocin injections to reduce stress? wink wink]

ACTH causes the adrenal gland to produce what important steroid "stress" hormone?
Correct Answer Cortisol

Lactotrophs release this hormone Correct Answer Prolactin (PRL)

What hormone is also known as prolactin inhibitory hormone? Correct Answer
Dopamine --> regulates milk production by inhibiting PRL

Prolactin inhibits the release of what hormone? Correct Answer Gonadotropin-releasing
hormone (GnRH)

What is the main way that production of prolactin is stimulated? Correct Answer Cute
little breastfeeding baby stimulating nipple mechanoreceptors

Thyrotrophs release what hormone? Correct Answer Thyroid-stimulating hormone
(TSH)

TSH is inhibited by a few hormones including: Correct Answer 1. T3
2. T4
3. Somatostatin

Somatostatin inhibits TSH from being released from the anterior pituitary. What other
hormone does it prevent from being released from the anterior pituitary? Correct
Answer Growth hormone

Somatotrophs release what hormone? Correct Answer Growth hormone

Growth hormone-releasing hormone (GHRH) and Somatostatin affect cAMP levels
different. Which increases cAMP and which decreases cAMP? Correct Answer GHRH
increases cAMP and stimulates GH production while Somatostatin decreases cAMP
and inhibits GH

What does cortisol bind to have an ANTAGONIST effect? Correct Answer OMG TRICK
QUESTION CORTISOL ALWAYS HAS AN AGONIST EFFECT (at least according to
that one figure...)

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