©SOPHIABENNET@2024/2025 Tuesday, August 20, 2024 10:21 AM
USMLE Step 1 Rapid Review Questions and
Answers (100% Pass)
abdominal pain, ascites, hepatomegaly - Answer✔️✔️-Budd-Chiari
syndrome
Familial hypercholesterolemia - Answer✔️✔️-achilles tendon xanthoma
adrenal hemorrhage, hypotension, DIC - Answer✔️✔️-Waterhouse-
Friderichsen syndrome
biochemistry of Marfan's syndrome - Answer✔️✔️-fibrillin defect
posthepatic venous thrombosis - Answer✔️✔️-Budd-Chiari syndrome
Familial hypercholesterolemia biochemistry - Answer✔️✔️-decrease in LDL
receptor signaling
Waterhouse-Friderichsen syndrome cause - Answer✔️✔️-meningococcemia
arachnodactyly, lens dislocation, aortic dissection, hyperflexible joints -
Answer✔️✔️-Marfan's syndrome
Athlete with polycythemia - Answer✔️✔️-EPO injection
Pott's disease - Answer✔️✔️-vertebral TB
Pott's disease clinical presentation - Answer✔️✔️-back pain, fever, night
sweats, weight loss
1
, ©SOPHIABENNET@2024/2025 Tuesday, August 20, 2024 10:21 AM
Sarcoidosis main histological presentation - Answer✔️✔️-noncaseating
granuloma
bilateral hilar adenopathy + uveitis - Answer✔️✔️-sarcoidosis
Osteogenesis imperfecta - Answer✔️✔️-type I collagen defect
Blue sclera indicate what? - Answer✔️✔️-osteogenesis imperfecta
Burton's line indicates what? - Answer✔️✔️-lead poisoning
Burton's line - Answer✔️✔️-bluish line on gingiva
Paget's disease of the bone biochemistry - Answer✔️✔️-increase in
osteoblastic and osteoclastic activity
bone pain, bone enlargement, arthritis - Answer✔️✔️-Paget's disease of the
bone
bounding pulses, diastolic heart murmur, head bobbing - Answer✔️✔️-
aortic regurgitation
butterfly facial rash, Raynaud's phenomenon in a young female -
Answer✔️✔️-SLE
Neurofibromatosis type I associated with what malignancies - Answer✔️✔️-
pheochromocytoma, optic gliomas
cafe-au-lait spots and Lisch nodules - Answer✔️✔️-Neurofibromatosis type I
Lisch nodules - Answer✔️✔️-iris hemartoma
2
, ©SOPHIABENNET@2024/2025 Tuesday, August 20, 2024 10:21 AM
McCune-Albright syndrome biochemistry - Answer✔️✔️-mosaic continuous
activation of stimulatory G protein
cafe-au-lait spots, polyostotic fibrous dysplasia, precocious puberty,
multiple endocrine abnormalities - Answer✔️✔️-McCune-Albright
syndrome
Duchenne's muscular dystrophy - Answer✔️✔️-X-linked recessive deletion
of dystrophin gene
Calf pseduohypertrophy - Answer✔️✔️-Duchenne's muscular dystrophy
clinical sign of Tay-Sach's, Niemann-Pick, or central retinal artery occlusion
- Answer✔️✔️-Cherry-red spot on macula
ganglioside accumulation - Answer✔️✔️-Tay-Sach's
sphingomyelin accumulation - Answer✔️✔️-Niemann-Pick disease
Stable angina - Answer✔️✔️-with moderate exercise
Unstable angina - Answer✔️✔️-with minimal exertion
Angina - Answer✔️✔️-chest pain on exertion
autoimmune-mediated post-MI fibrinous pericarditis 1-12 weeks after
acute episode - Answer✔️✔️-Dressler syndrome
Chest pain, pericardial effusion, friction rub, persistent fever following MI
1-12 weeks after - Answer✔️✔️-Dressler's syndrome
3
, ©SOPHIABENNET@2024/2025 Tuesday, August 20, 2024 10:21 AM
Gowers' sign associated with what disease? - Answer✔️✔️-Duchenne
muscular dystrophy
Gower's sign definition - Answer✔️✔️-child uses arms to stand up from
squat
"Slapped cheeks" - Answer✔️✔️-erythema infectiosum/fifth disease
Erythema infectiosum/fifth disease - Answer✔️✔️-parvovirus B19
child with fever later develops red rash on face that spreads to body -
Answer✔️✔️-erythema infectiosum/fifth disease
autosomal-dominant CAG repeat expansion - Answer✔️✔️-Huntington's
disease
chorea, dementia, caudate degeneration - Answer✔️✔️-Huntington's disease
muscle glycogen phosphorylase deficiency - Answer✔️✔️-McArdle's
syndrome
chronic exercise intolerance with myalgia, fatigue, painful cramps,
myoglobinuria - Answer✔️✔️-McArdle's disease
Cold intolerance may suggest what diagnosis? - Answer✔️✔️-
hypothyroidism
Lesion that causes internuclear ophthalmoplegia - Answer✔️✔️-damage to
MLF
4
USMLE Step 1 Rapid Review Questions and
Answers (100% Pass)
abdominal pain, ascites, hepatomegaly - Answer✔️✔️-Budd-Chiari
syndrome
Familial hypercholesterolemia - Answer✔️✔️-achilles tendon xanthoma
adrenal hemorrhage, hypotension, DIC - Answer✔️✔️-Waterhouse-
Friderichsen syndrome
biochemistry of Marfan's syndrome - Answer✔️✔️-fibrillin defect
posthepatic venous thrombosis - Answer✔️✔️-Budd-Chiari syndrome
Familial hypercholesterolemia biochemistry - Answer✔️✔️-decrease in LDL
receptor signaling
Waterhouse-Friderichsen syndrome cause - Answer✔️✔️-meningococcemia
arachnodactyly, lens dislocation, aortic dissection, hyperflexible joints -
Answer✔️✔️-Marfan's syndrome
Athlete with polycythemia - Answer✔️✔️-EPO injection
Pott's disease - Answer✔️✔️-vertebral TB
Pott's disease clinical presentation - Answer✔️✔️-back pain, fever, night
sweats, weight loss
1
, ©SOPHIABENNET@2024/2025 Tuesday, August 20, 2024 10:21 AM
Sarcoidosis main histological presentation - Answer✔️✔️-noncaseating
granuloma
bilateral hilar adenopathy + uveitis - Answer✔️✔️-sarcoidosis
Osteogenesis imperfecta - Answer✔️✔️-type I collagen defect
Blue sclera indicate what? - Answer✔️✔️-osteogenesis imperfecta
Burton's line indicates what? - Answer✔️✔️-lead poisoning
Burton's line - Answer✔️✔️-bluish line on gingiva
Paget's disease of the bone biochemistry - Answer✔️✔️-increase in
osteoblastic and osteoclastic activity
bone pain, bone enlargement, arthritis - Answer✔️✔️-Paget's disease of the
bone
bounding pulses, diastolic heart murmur, head bobbing - Answer✔️✔️-
aortic regurgitation
butterfly facial rash, Raynaud's phenomenon in a young female -
Answer✔️✔️-SLE
Neurofibromatosis type I associated with what malignancies - Answer✔️✔️-
pheochromocytoma, optic gliomas
cafe-au-lait spots and Lisch nodules - Answer✔️✔️-Neurofibromatosis type I
Lisch nodules - Answer✔️✔️-iris hemartoma
2
, ©SOPHIABENNET@2024/2025 Tuesday, August 20, 2024 10:21 AM
McCune-Albright syndrome biochemistry - Answer✔️✔️-mosaic continuous
activation of stimulatory G protein
cafe-au-lait spots, polyostotic fibrous dysplasia, precocious puberty,
multiple endocrine abnormalities - Answer✔️✔️-McCune-Albright
syndrome
Duchenne's muscular dystrophy - Answer✔️✔️-X-linked recessive deletion
of dystrophin gene
Calf pseduohypertrophy - Answer✔️✔️-Duchenne's muscular dystrophy
clinical sign of Tay-Sach's, Niemann-Pick, or central retinal artery occlusion
- Answer✔️✔️-Cherry-red spot on macula
ganglioside accumulation - Answer✔️✔️-Tay-Sach's
sphingomyelin accumulation - Answer✔️✔️-Niemann-Pick disease
Stable angina - Answer✔️✔️-with moderate exercise
Unstable angina - Answer✔️✔️-with minimal exertion
Angina - Answer✔️✔️-chest pain on exertion
autoimmune-mediated post-MI fibrinous pericarditis 1-12 weeks after
acute episode - Answer✔️✔️-Dressler syndrome
Chest pain, pericardial effusion, friction rub, persistent fever following MI
1-12 weeks after - Answer✔️✔️-Dressler's syndrome
3
, ©SOPHIABENNET@2024/2025 Tuesday, August 20, 2024 10:21 AM
Gowers' sign associated with what disease? - Answer✔️✔️-Duchenne
muscular dystrophy
Gower's sign definition - Answer✔️✔️-child uses arms to stand up from
squat
"Slapped cheeks" - Answer✔️✔️-erythema infectiosum/fifth disease
Erythema infectiosum/fifth disease - Answer✔️✔️-parvovirus B19
child with fever later develops red rash on face that spreads to body -
Answer✔️✔️-erythema infectiosum/fifth disease
autosomal-dominant CAG repeat expansion - Answer✔️✔️-Huntington's
disease
chorea, dementia, caudate degeneration - Answer✔️✔️-Huntington's disease
muscle glycogen phosphorylase deficiency - Answer✔️✔️-McArdle's
syndrome
chronic exercise intolerance with myalgia, fatigue, painful cramps,
myoglobinuria - Answer✔️✔️-McArdle's disease
Cold intolerance may suggest what diagnosis? - Answer✔️✔️-
hypothyroidism
Lesion that causes internuclear ophthalmoplegia - Answer✔️✔️-damage to
MLF
4
