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USMLE Step 1 Rapid Review Practice Questions and Answers (100% Pass)

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USMLE Step 1 Rapid Review Practice Questions and Answers (100% Pass) Abdominal pain, ascites, hepatomegaly, (also high D dimer, CHF without JVD) - Answer️️ -Budd-Chiari syndrome Achilles tendon xanthoma - Answer️️ -Familial hypercholesterolemia Adrenal hemorrhage, hypotension, DIC - Answer️️ -Waterhouse- Friderichsen syndrome (meningococcemia) Arachnodactyly, lens dislocation, aortic dissection, hyperflexible joints - Answer️️ -Marfan's (fibrillin defect) Athlete with polycythemia - Answer️️ -Erythropoietin injection Back pain, fever, night sweats, weight loss - Answer️️ -Pott's (TB to the vertebrae) Bilateral hilar adenopathy, uveitis - Answer️️ -Sarcoid Blue sclera - Answer️️ -Osteogenesis imperfecta Bluish line on gingiva - Answer️️ -Burton's line - lead poisoning Bone pain, bone enlargement, arthritis, (also increased hat size, fracture, increased alk phos) - Answer️️ -Paget's Bounding pulses, diastolic hear murmur, head bobbing - Answer️️ - Aortic regurg ©SOPHIABENNET@2024/2025 Tuesday, August 20, 2024 10:21 AM 2 Café-au-lait spots, Lisch nodules - Answer️️ -NF (1 = optic glimoas and pheo, 2 = acoustic Schwannomas) Café-au-lait spots, polyostotic fibrous dysplasia, precocious puberty - Answer️️ -McCune-Albright syndome (G protein problem) Calf pseudohypertrophy - Answer️️ -Duchenne's muscular dystrophy Cherry-red spot on macula - Answer️️ -Tay-Sachs, Niemann-Pick, central retinal artery occlusion Chest pain, pericardial effusion/friction rub, persistent fever following MI - Answer️️ -Dressler's (autoimmune post-MI) Child uses arms to stand up from squat - Answer️️ -Gower's sign (Duchenne's) Child with fever develops red rash on face that spreads to body - Answer️️ -Slapped cheek - B19 Chorea, dementia, caudate degeneration - Answer️️ -Huntington

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©SOPHIABENNET@2024/2025 Tuesday, August 20, 2024 10:21 AM


USMLE Step 1 Rapid Review Practice
Questions and Answers (100% Pass)

Abdominal pain, ascites, hepatomegaly, (also high D dimer, CHF without
JVD) - Answer✔️✔️-Budd-Chiari syndrome

Achilles tendon xanthoma - Answer✔️✔️-Familial hypercholesterolemia

Adrenal hemorrhage, hypotension, DIC - Answer✔️✔️-Waterhouse-
Friderichsen syndrome (meningococcemia)

Arachnodactyly, lens dislocation, aortic dissection, hyperflexible joints -
Answer✔️✔️-Marfan's (fibrillin defect)

Athlete with polycythemia - Answer✔️✔️-Erythropoietin injection

Back pain, fever, night sweats, weight loss - Answer✔️✔️-Pott's (TB to the
vertebrae)

Bilateral hilar adenopathy, uveitis - Answer✔️✔️-Sarcoid

Blue sclera - Answer✔️✔️-Osteogenesis imperfecta

Bluish line on gingiva - Answer✔️✔️-Burton's line - lead poisoning

Bone pain, bone enlargement, arthritis, (also increased hat size, fracture,
increased alk phos) - Answer✔️✔️-Paget's

Bounding pulses, diastolic hear murmur, head bobbing - Answer✔️✔️-
Aortic regurg



1

, ©SOPHIABENNET@2024/2025 Tuesday, August 20, 2024 10:21 AM

Café-au-lait spots, Lisch nodules - Answer✔️✔️-NF (1 = optic glimoas and
pheo, 2 = acoustic Schwannomas)

Café-au-lait spots, polyostotic fibrous dysplasia, precocious puberty -
Answer✔️✔️-McCune-Albright syndome (G protein problem)

Calf pseudohypertrophy - Answer✔️✔️-Duchenne's muscular dystrophy

Cherry-red spot on macula - Answer✔️✔️-Tay-Sachs, Niemann-Pick, central
retinal artery occlusion

Chest pain, pericardial effusion/friction rub, persistent fever following MI
- Answer✔️✔️-Dressler's (autoimmune post-MI)

Child uses arms to stand up from squat - Answer✔️✔️-Gower's sign
(Duchenne's)

Child with fever develops red rash on face that spreads to body -
Answer✔️✔️-Slapped cheek - B19

Chorea, dementia, caudate degeneration - Answer✔️✔️-Huntington's

Chronic exercise intolerance with myalgia, fatigue, painful cramps -
Answer✔️✔️-McArdle's (muscle phosphorylase deficiency)

Cold intolerance - Answer✔️✔️-Hypothyroidism

Conjugate lateral gaze palsy, horizontal diplopia - Answer✔️✔️-Internuclear
ophthalmoplegia (MS or stroke)

Continuous machinery heart murmur - Answer✔️✔️-PDA



2

, ©SOPHIABENNET@2024/2025 Tuesday, August 20, 2024 10:21 AM

Cutaneous/dermal edema due to CT expansion - Answer✔️✔️-Myxedema

Dark purple skin / mouth nodules - Answer✔️✔️-Kaposi's sarcoma

Deep, labored breathing / hyperventilation - Answer✔️✔️-Kussmaul
breathing, DKA

Dermatitis, dementia, diarrhea - Answer✔️✔️-Pellagra (B3 / niacin
deficiency)

Dilated cardiomyopathy, edema, polyneuropathy - Answer✔️✔️-Wet
beriberi (B1 / thiamine deficiency)

Dog or cat bite resulting in infection - Answer✔️✔️-Pasteurella multocida
(local cellulitis)

Dry eyes, dry mouth, arthritis - Answer✔️✔️-Sjogren's syndrome

Dysphagia (esophageal webs), glossitis (smooth tongue), iron deficiency
anemia - Answer✔️✔️-Plummer-Vinson syndrome

Elastic skin, hypermobility of joints - Answer✔️✔️-Ehler-Danlos (type III
collagen)

Enlarged. hard left supraclavicular node - Answer✔️✔️-VIrchow's node
(abdominal met)

Erythroderma, lymphadenopathy, hepatosplenomegaly, atypical T cells -
Answer✔️✔️-Sezary syndrome (cutaneous T cell lymphoma)




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