Applied Patho for the Advanced
Practice Nurse (Dulgasch)- Chapter 1
1;4 - ANSWER After Meiosis, ovum produces how many daughter cells? ____
sperm produces how many daughter cells? ____
1. carcinoma (epithelial)
2. sarcoma (connective)
3. leukemia/lymphoma (hematopoetic) - ANSWER three types of malignant tumors
20 years old - ANSWER What is the common age of clinical manifestation of Type 2
Neurofibromatosis?
40 years old - ANSWER What is the average age of clinical manifestation of
Schawnnomatosis?
5 years old - ANSWER average age of death in Tay-Sachs disease is?
acetylation (enzyme is acetyltransferase) - ANSWER process of histone uncoiling that
involves an enzyme
-uncoiling is required for to allow access for transcription for the expression of genes (turn on)
Acetylcholine - ANSWER neurotransmitter that stimulates muscle fiber contraction
Acquired mutations - ANSWER occur in somatic cells and do not affect all the cells in the
body. Not inherited
Acquired mutations (inherited only account for 5-15% of cancers) - ANSWER Which is more
common mutations for cancer?
Genetic (germline) or Acquired (somatic)
Active transport - ANSWER movement from low concentration to high concentration
against a concentration gradient
-uses carrier molecule
, Applied Patho for the Advanced
Practice Nurse (Dulgasch)- Chapter 1
-Energy consumed
Active transport example - ANSWER example = Sodium Potassium Pump
adapt - ANSWER cells _________ to attempt defying death from environmental factors;
goal is to achieve homeostasis
Allele - ANSWER base pair variation
Anaphase - ANSWER Phase of mitosis; Chromosomes separate and move to opposite ends
of the cell
Anaplasia - ANSWER loss of differentiation that occurs with cells
angiogenesis - ANSWER growth of new blood vessels (often seen in cancers to help supply
oxygen and nutrients to the new tumor)
Apoptosis - ANSWER programmed cell death
atrophy - ANSWER occurs due to decreased work demands on the cell; decrease in size and
number
-causes include: disuse, denervation, endocrine hypofunction, inadequate nutrition, and ischemia
Autosomal Dominant disorders - ANSWER - monogenic disorders
- passed from parent to child regardless of gender
- occurs with both homozygous and heterozygous pairs
ex. Marfan syndrome and Neurofibromatosis
Autosomal Recessive Disorders - ANSWER - monogenic
- passed from both parents to child regardless of gender
Practice Nurse (Dulgasch)- Chapter 1
1;4 - ANSWER After Meiosis, ovum produces how many daughter cells? ____
sperm produces how many daughter cells? ____
1. carcinoma (epithelial)
2. sarcoma (connective)
3. leukemia/lymphoma (hematopoetic) - ANSWER three types of malignant tumors
20 years old - ANSWER What is the common age of clinical manifestation of Type 2
Neurofibromatosis?
40 years old - ANSWER What is the average age of clinical manifestation of
Schawnnomatosis?
5 years old - ANSWER average age of death in Tay-Sachs disease is?
acetylation (enzyme is acetyltransferase) - ANSWER process of histone uncoiling that
involves an enzyme
-uncoiling is required for to allow access for transcription for the expression of genes (turn on)
Acetylcholine - ANSWER neurotransmitter that stimulates muscle fiber contraction
Acquired mutations - ANSWER occur in somatic cells and do not affect all the cells in the
body. Not inherited
Acquired mutations (inherited only account for 5-15% of cancers) - ANSWER Which is more
common mutations for cancer?
Genetic (germline) or Acquired (somatic)
Active transport - ANSWER movement from low concentration to high concentration
against a concentration gradient
-uses carrier molecule
, Applied Patho for the Advanced
Practice Nurse (Dulgasch)- Chapter 1
-Energy consumed
Active transport example - ANSWER example = Sodium Potassium Pump
adapt - ANSWER cells _________ to attempt defying death from environmental factors;
goal is to achieve homeostasis
Allele - ANSWER base pair variation
Anaphase - ANSWER Phase of mitosis; Chromosomes separate and move to opposite ends
of the cell
Anaplasia - ANSWER loss of differentiation that occurs with cells
angiogenesis - ANSWER growth of new blood vessels (often seen in cancers to help supply
oxygen and nutrients to the new tumor)
Apoptosis - ANSWER programmed cell death
atrophy - ANSWER occurs due to decreased work demands on the cell; decrease in size and
number
-causes include: disuse, denervation, endocrine hypofunction, inadequate nutrition, and ischemia
Autosomal Dominant disorders - ANSWER - monogenic disorders
- passed from parent to child regardless of gender
- occurs with both homozygous and heterozygous pairs
ex. Marfan syndrome and Neurofibromatosis
Autosomal Recessive Disorders - ANSWER - monogenic
- passed from both parents to child regardless of gender
