ASCP Coagulation & Hemostasis Exam Questions and Complete Solutions Graded A+

ASCP Coagulation &
Hemostasis Exam
Questions and Complete
Solutions Graded A+

Denning [Date] [Course title]

, Primary hemostasis - Answer: Vasoconstriction

platelet adhesion

platelet aggregation to form hemostatic plug at injury site



Secondary hemostasis - Answer: interaction of coag factors to produce fibrin

fibrin stabilization by factor XIII



Fibrinolysis - Answer: release of plasminogen activator

conversion of plasminogen to plasmin

conversion of fibrin to fibrin degradation products



Prothrombin time (PT) - Answer: Used to detect the deficiencies in the EXTRINSIC & COMMON
pathways. Monitor COUMADIN (warfarin) therapy. Use along w/ INR

(II,VII,X,V,I)

Can be stored for up to 4 hours at 4C



Activated Partial Thromboplastin time (APTT) - Answer: Used to detect deficiencies in the INTRINSIC &
COMMON pathways. Monitor using HEPARIN

(V,X,VIII,IX,XI,XII,PK,I,II)



D-Dimer - Answer: Used as a marker for DIC



Factor VII deficiency - Answer: Prolonged PT ; normal APTT



Factors PK,XII,XI,IX,VIII deficiencies - Answer: normal PT; prolonged APTT



Factor X,V,II,I deficiency - Answer: prolonged PT; prolonged APTT



Removal of the spleen - Answer: This might be the last resort in a patient ITP...