1. MAOIs (monoamine oxidase inhibitors) affect which neurotransmitters?
s s s s s s
A. Serotonin, Dopamine, Norepinephrine
s s
B. Serotonin, GABA, Glutamate s s
C. Acetylcholine, Dopamine, Norepinephrine s s
D. Dopamine, GABA, Acetylcholine: A. Serotonin, Dopamine, Norepinephrine
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2. Which of the following is considered first line treatment for depression?
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A. SSRI
B. FGA
C. SNRI
D. MAOI: A. SSRI s s
3. When treating a patient for major depression disorder which medication
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would the PMHNP consider first?
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A. Depakote
B. Selegiline
C. Escitalopram
D. Isocarboxazid: C. Escitalopram s s
4. Which of the following medication should be considered for a patient diag-
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nosed with major depressive disorder who reports "always forgetting to take
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my pills"?
s
A. Mirtazapine
B. Fluvoxamine
C. Fluoxetine
D. Carbemazepine: C. Fluoxetine s s
5. Which of the following medication has a black box warning of a life-threat-
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ening skin rash?
s s s
A. Lithium
B. Lamotrigine
C. Lurasidone
D. Lorazepam: B. Lamotrigine s s
6. Which medication is considered the best tolerated SSRI?
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A. Venlafaxine
B. Bupropion
,C. Setraline
D. Escitalopram: D. Escitalopram s s
7. During a 4 week follow up appointment, Rashida, who is prescribed Ser-
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traline 25mg qAM reports slight improvement in depression symptoms andt
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olerating medication well. Which of the following should the PMHNP do?
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A. Increase Setraline dose s s
B. Switch to an SNRI s s s
C. Switch to a different SSRI s s s s
D. Add Trazodone qHS for sleep.: A. Increase Setraline dose
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8. Which medication should be avoided for the 66 year patient diagnosed with
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major depressive disorder and anxiety with a reported fall 3 months ago?
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A. Citalopram
B. Setraline
C. Paroxetine
D. Aripiprazole: C. Paroxetine s s
9. A patient reports upset stomach and diarrhea 3 days after taking new pre-
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scription of sertraline.Which of the following is the most appropriate responsefr
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om the PMHNP?
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A. "Start doubling the dose of sertraline and your symptoms will begin to easeu
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p".
B. "Most side effects subside after 4- s s s s s
5 days. Your body is getting adjusted tothe increased serotonin levels".
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C. "Stop taking it immediately and go to the local emergency department".
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D. "You must take Sertraline with food, otherwise you will continue to expe-
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rience GI symptoms".: B. "Most side effects subside after 4-
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5 days. Your body isgetting adjusted to the increased serotonin levels".
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10. During a 2 week follow up appointment, the patient reports no improve-
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sment in depressive symptoms with escitalopram.Which of the following state-
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ment made by the PMHNP is correct?
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A. "Let's discontinue escitalopram and start you on something stronger".
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B. "It can take up to 6 weeks before you notice improvements of depressives
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ymptoms".
C. "I am going to prescibe Trazodone. Take it at night to help you sleep".
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D. "Start taking two pills at a time".: B. "It can take up to 6 weeks before you noticeim
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provements of depressive symptoms". s s s
, 11. Duloxetine effects which two neurotransmitters? s s s s
A. serotonin and norepinephrine s s
B. serotonin and dopamine s s
C. norepinephrine and GABA s s
D. glutamate and acetylcholine: A. serotonin and norepinephrine
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12. Awura, a 70 year old patient diagnosed with major depressive disorder re
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ports a recent 40 pound weight loss within the last 3 months. Which med-
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ication should the PMHNP consider adding to her medication regimen?
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A. quetiapine
B. mirtazpine
C. valproic acid s
D. paroxetine: B. mirtazpine s s
13. Which of the following symptoms is NOT an adverse effect associated witht
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he acute use of opioids?
s s s s
A. Sedation
B. Respiratory depression s
C. Immunosuppression
D. Itching: C. Immunosuppressions s
14. When dosing citalopram for Lynee, a 72 year old patient, the PMHNPu
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nderstands to dose at 1/2 dose due to the increased risk of
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A. delirium
B. polypharmacy
C. falls
D. QTc prolongation: D. QTc prolongation
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15. Which of the following medication class is approved for first line treatmentf
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or OCD? s
A. Atypical antipsychotics s
B. Benzodiazepines
C. MAOI
D. SSRI: D. SSRI s s
16. Which SSRI has a mild antihistamine effect?
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A. Paroxetine
B. Fluoxetine