Complete Final Review |Actual Exam |
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,1. Medications for depression SSRIs
SNRIs
SDRIs
TCAs
MAOI
s
2. SSRIs -Action: inhibit 5-HT reuptake
-Examples: citalopram,
escitalopram, flu- oxetine,
paroxetine, sertraline
-Adverse effects:
•nausea
•agitation
•diarrhea
•headache
•weight gain
•sexual side effects
3. SNRIs -inhibit 5-HT reuptake
-inhibit NE reuptake (‘ energy, focus)
-increase DA in prefrontal cortex (‘
cogni- tion)
-Examples: desvenlafaxine,
duloxetine, levomilnacipran,
venlafaxine
-Adverse effects:
•elevated blood pressure
•nausea
•sweating
•tremors
•anxiety
•insomnia
•constipation
•anorexia
•sexual dysfunction
4. SDRIs -inhibit DA reuptake (‘alertness,
motivation)
2/
,-inhibit NE reuptake (‘energy)
-Adverse effects:
•agitation
•headache
3/
, •dry mouth
•constipation
•weight loss
5. TCAs -Action: inhibits the reuptake of
serotonin and norepinephrine;
blocks norepineph- rine, histamine,
and acetylcholine recep- tors
-Examples: amitriptyline,
clomipramine, desipramine,
doxepin
-Common Side Effects:
•dry mouth
•constipation
•blurred vision
•urinary retention
•sedation
•weight gain
•hypotension
•tachycardia
•sexual dysfunction
6. MAOIs -Action: increases norepinephrine
and serotonin by inhibiting the
enzyme that in- activates it
-Examples: isocarboxazid,
phenelzine, tranylcypromine
-Common Side Effects:
•sedation
•dizziness
•sexual dysfunction
•hypertensive crisis
7. Prescribing pearls: fluoxetine (Prozac)
citalopram (Celexa)
8. Prescribing pearls:
escitalo- pram (Lexapro)
9. Prescribing pearls:
4/