) Advanced Pharmacology
Fundamentals | Exam Guide
Review| 100% Correct | Grade A -
Chamberlain
Question:
A woman who is taking Pioglitazone states, "I'm glad that this medication
promotes weight loss."
Answer:
First this medication promotes increase in LDL levels, which increases
cardiovascular risk. Also, she's a female so speak about exercise and weight
bearing exercise d/t possible increased risk for fractures.
Question:
Glucocorticoid MOA
Answer:
Most effective in long-term control of airway inflammation
,Question:
Cromolyn MOA
Answer:
Used as prophylaxis for mild to moderate asthma
Question:
Monoclonal Antibodies MOA
Answer:
Used for allergy-related asthma and Eosinophilic asthma. Omalizumab for
allergy related and Ben ralizumab, mepliz, and resliz are for eosinophilic
Question:
Leukotriene MOA
Answer:
Second-line therapy to reduce inflammation and bronchoconstriction
Question:
B2 adrenergic agonists MOA
Answer:
Can be used PRN, for EIB, COPD exacerbations, and maintenance therapy
,Question:
methylxanthines MOA
Answer:
Maintenance therapy for chronic stable asthma (theophylline). P. 570. Use
ONLY if B2 or anticholinergics are not appropriate.
Question:
anticholinergic MOA
Answer:
Approved for bronchospasm related to COPD
Question:
•What are some risk factors of fatal asthma attacks?
Answer:
Uncontrolled, hospitalized recently, triggers,
Question:
What pt education can you provide a patient for ICS use?
Answer:
Rinse d/t oropharyngeal candidiasis and dysphonia (hoarseness, difficulty
speaking).
, Question:
Roflumilast (select all that apply)
a) Reduces inflammation
b) Not intended during pregnancy
c) Approved for asthma
d) First-line drug for COPD
Answer:
Reduces inflammation, not intended for pregnancy, approved only for COPD,
Second-line drug for COPD
Uses for exacerbations prophylaxis in pts with severe COPD with a primary
chronic bronchitis component.
Question:
What patient teaching can a provider give when prescribing a PPI?
Answer:
Hypomagnesia symptoms: muscle cramps, tremors, cramps, and palpitations.
Check Mg levels periodically especially in the elderly. Get enough calcium and
VIT D. call if having diarrhea (Cdiff)