Excelsior Pathophysiology UPDATED
Exam Questions and CORRECT Answers
Which sign is a result of ischemia or prolonged immobilization of the legs? - CORRECT
ANSWER- Reduction in circumference of both calves; muscle wasting occurs with ischemia
and immobilization and so the calf muscles will atrophy and decrease in size.
Why is fat necrosis a complication of pancreatitis? - CORRECT ANSWER- The pancreas
produces lipase; Lipases, released as a result of pancreatitic acinar cell injury in pancreatitis,
act on fat to convert triglycerides to fatty acids.
Which is an X-linked single-gene disorder? - CORRECT ANSWER- Hemophilia
How does pain from a malignant neoplasm differ from nonmalignant chronic pain? -
CORRECT ANSWER- Pain from a malignant neoplasm can be reduced by reducing fear.
What is common to all tumor suppressor genes? - CORRECT ANSWER- Tumor suppressor
genes inhibit cell proliferation.; The function of yumor suppressor genes is to interrupt the
cell cycle to allow for reapair of damaged DNA.
During the healing of a burn wound, which part of the inflammation response must be
managed in order to avoid burn shock? - CORRECT ANSWER- Histamine release must be
controlled to prevent increased capillary permeability and it contributes to blood volume loss
and burn shock.
What is the greatest risk factor for a person who is immunocompromised? - CORRECT
ANSWER- Opportunistic infections by ones own normal flora
Which leukemia is the most common malignancy in children? - CORRECT ANSWER- Acute
lymphocytic leukemia (ALL); it is seen mostly in children between the ages of 3 and 7
Which disorder typically presents with skin thickening and connective tissue deposition that
result in severe fibrosis? - CORRECT ANSWER- Sclaroderma; it is a multisystem
inflammatory disease of connective tissue characterized by skin thickening and deposits of
large quantities of connective tissue that lead to severe fibrosis.
, The presence of tarry, black feces in a newborn suggest which abnormaility? - CORRECT
ANSWER- Vitamin K deficiency; deficiency of vitamin K results in decreased vitamin k-
dependent clotting factors and bleeding in the digestive tract, which leads to black tarry
stools.
which condition results in red blood cell destruction that leads to anemia? - CORRECT
ANSWER- Drug-induced hemolysis
what is an example of type IV delayed hypersensitivity? - CORRECT ANSWER- Contact
dermatitis
Which statement best describes the underlying causes of Wiskott-Aldrich syndrome? -
CORRECT ANSWER- An X-linked deficiency which affects cell signaling and cytoskeletal
organization.
Secondary Hypertension - CORRECT ANSWER- Increased blood pressure that is caused by
another known condition; is most often related to renal disease
Vegatative growths on myocardial valves characterize which type of myocardial disorder? -
CORRECT ANSWER- Infective endocarditis; myocardial infection is characherized by
heavy bacterial colonization of cardiac valves.
which manifestations are typically associated with left-sided congestive heart failure? -
CORRECT ANSWER- Dyspnea, oliguria, and crackles
Distended neck veins and pulsus paradoxus are seen in whcih disorder? - CORRECT
ANSWER- Cardiac tamponade
what are the necessary requirements for automaticity in SA nodal cells? - CORRECT
ANSWER- ion channels in phase 4 must open spontaneously due to hyperpolarization in
phase 3
Which condition is best defined as an iflammation in a vein accompanied by thrombus? -
CORRECT ANSWER- Thrombophlebitis
Exam Questions and CORRECT Answers
Which sign is a result of ischemia or prolonged immobilization of the legs? - CORRECT
ANSWER- Reduction in circumference of both calves; muscle wasting occurs with ischemia
and immobilization and so the calf muscles will atrophy and decrease in size.
Why is fat necrosis a complication of pancreatitis? - CORRECT ANSWER- The pancreas
produces lipase; Lipases, released as a result of pancreatitic acinar cell injury in pancreatitis,
act on fat to convert triglycerides to fatty acids.
Which is an X-linked single-gene disorder? - CORRECT ANSWER- Hemophilia
How does pain from a malignant neoplasm differ from nonmalignant chronic pain? -
CORRECT ANSWER- Pain from a malignant neoplasm can be reduced by reducing fear.
What is common to all tumor suppressor genes? - CORRECT ANSWER- Tumor suppressor
genes inhibit cell proliferation.; The function of yumor suppressor genes is to interrupt the
cell cycle to allow for reapair of damaged DNA.
During the healing of a burn wound, which part of the inflammation response must be
managed in order to avoid burn shock? - CORRECT ANSWER- Histamine release must be
controlled to prevent increased capillary permeability and it contributes to blood volume loss
and burn shock.
What is the greatest risk factor for a person who is immunocompromised? - CORRECT
ANSWER- Opportunistic infections by ones own normal flora
Which leukemia is the most common malignancy in children? - CORRECT ANSWER- Acute
lymphocytic leukemia (ALL); it is seen mostly in children between the ages of 3 and 7
Which disorder typically presents with skin thickening and connective tissue deposition that
result in severe fibrosis? - CORRECT ANSWER- Sclaroderma; it is a multisystem
inflammatory disease of connective tissue characterized by skin thickening and deposits of
large quantities of connective tissue that lead to severe fibrosis.
, The presence of tarry, black feces in a newborn suggest which abnormaility? - CORRECT
ANSWER- Vitamin K deficiency; deficiency of vitamin K results in decreased vitamin k-
dependent clotting factors and bleeding in the digestive tract, which leads to black tarry
stools.
which condition results in red blood cell destruction that leads to anemia? - CORRECT
ANSWER- Drug-induced hemolysis
what is an example of type IV delayed hypersensitivity? - CORRECT ANSWER- Contact
dermatitis
Which statement best describes the underlying causes of Wiskott-Aldrich syndrome? -
CORRECT ANSWER- An X-linked deficiency which affects cell signaling and cytoskeletal
organization.
Secondary Hypertension - CORRECT ANSWER- Increased blood pressure that is caused by
another known condition; is most often related to renal disease
Vegatative growths on myocardial valves characterize which type of myocardial disorder? -
CORRECT ANSWER- Infective endocarditis; myocardial infection is characherized by
heavy bacterial colonization of cardiac valves.
which manifestations are typically associated with left-sided congestive heart failure? -
CORRECT ANSWER- Dyspnea, oliguria, and crackles
Distended neck veins and pulsus paradoxus are seen in whcih disorder? - CORRECT
ANSWER- Cardiac tamponade
what are the necessary requirements for automaticity in SA nodal cells? - CORRECT
ANSWER- ion channels in phase 4 must open spontaneously due to hyperpolarization in
phase 3
Which condition is best defined as an iflammation in a vein accompanied by thrombus? -
CORRECT ANSWER- Thrombophlebitis
