Practice Exam Questions and Answers
for SBB Course
Chemicals that send signals between cells are - CORRECT ANSWER-Cytokines
Antibodies are made by what cells? - CORRECT ANSWER-Plasma cells
Where do B cells mature? - CORRECT ANSWER-Bone Marrow
Where do T cells mature? - CORRECT ANSWER-Thymus
Coating of a cell with antibodies or complement is called? - CORRECT ANSWER-
Opsonization
CD4 + cells are? - CORRECT ANSWER-T helper cells
The specific chemical group that provokes an antibody response - CORRECT
ANSWER-Epitope
Blood groups are made of two main kinds of chemicals - CORRECT ANSWER-
Proteins, carbohydrates
What is the function of the FC piece of an immunoglobulin? - CORRECT ANSWER-
Monocyte binding
What is the only Ig that crosses the placenta? - CORRECT ANSWER-IgG
What does 2-ME OR DTT do to IgM antibodies? - CORRECT ANSWER-Destroys
disulfide bonds
Which is the secretory Ig? - CORRECT ANSWER-IgA
Which Ig is responsible for allergic reaction's? - CORRECT ANSWER-IgE
Which IgG subclass does not bind complement? - CORRECT ANSWER-IgG4
Which IgG sub classes are most clinically significant? - CORRECT ANSWER-IgG 1 & 3
What is isotype switching? - CORRECT ANSWER-Example IgM switches to IgG
What is the end point of complement activation? - CORRECT ANSWER-Hole in cell
, At what stage of complement cascade is it amplified? - CORRECT ANSWER-C3
activation
What two ions are needed for complement activity? - CORRECT ANSWER-Ca++ and
Mg++
Name two complement components that are anaphylatoxins - CORRECT ANSWER-
C3a and C5a
What is the minimum number of days a BBK specimen must be kept? - CORRECT
ANSWER-Seven days post transfusion
Name two groups for which weak D testing is required - CORRECT ANSWER-Donors,
NB of D- Moms
What is required for crossmatch specimen to be used longer than three days? -
CORRECT ANSWER-Known history, not pregnant or transfusion last three months
What can be used to neutralize heparin? - CORRECT ANSWER-Protamine sulfate
If given Rh positive cells to Rh negative person, what does standards require? -
CORRECT ANSWER-A policy?(and a Rhig policy)
Name three requirements for when blood must be irrradiated - CORRECT ANSWER-
TA-GVHD risk; blood relative; HLA-matched
Why can't you use an EDTA specimen for Donath Landsteiner test? - CORRECT
ANSWER-It wouldn't lyse C'
What is meant by thermal amplitude? - CORRECT ANSWER-How high temp of reaction
What is ZZAP? - CORRECT ANSWER-Ficin OR papain AND DDT
What concentration of albumin is used as a serum control? - CORRECT ANSWER-6%
What is the source Ficin? - CORRECT ANSWER-Fig
What lectin agglutinates ficin-treated cells? - CORRECT ANSWER-Glycine soja (soy
bean)
What is the specificity of Phaseolus lunatus lectin? - CORRECT ANSWER-A lima bean
All acquired B cells were originally what type? - CORRECT ANSWER-A
Glycine soja also agglutinates what types of polyagg? - CORRECT ANSWER-
T(bacterial, low sialic acid). Tn (mutation)(also A lectins)
for SBB Course
Chemicals that send signals between cells are - CORRECT ANSWER-Cytokines
Antibodies are made by what cells? - CORRECT ANSWER-Plasma cells
Where do B cells mature? - CORRECT ANSWER-Bone Marrow
Where do T cells mature? - CORRECT ANSWER-Thymus
Coating of a cell with antibodies or complement is called? - CORRECT ANSWER-
Opsonization
CD4 + cells are? - CORRECT ANSWER-T helper cells
The specific chemical group that provokes an antibody response - CORRECT
ANSWER-Epitope
Blood groups are made of two main kinds of chemicals - CORRECT ANSWER-
Proteins, carbohydrates
What is the function of the FC piece of an immunoglobulin? - CORRECT ANSWER-
Monocyte binding
What is the only Ig that crosses the placenta? - CORRECT ANSWER-IgG
What does 2-ME OR DTT do to IgM antibodies? - CORRECT ANSWER-Destroys
disulfide bonds
Which is the secretory Ig? - CORRECT ANSWER-IgA
Which Ig is responsible for allergic reaction's? - CORRECT ANSWER-IgE
Which IgG subclass does not bind complement? - CORRECT ANSWER-IgG4
Which IgG sub classes are most clinically significant? - CORRECT ANSWER-IgG 1 & 3
What is isotype switching? - CORRECT ANSWER-Example IgM switches to IgG
What is the end point of complement activation? - CORRECT ANSWER-Hole in cell
, At what stage of complement cascade is it amplified? - CORRECT ANSWER-C3
activation
What two ions are needed for complement activity? - CORRECT ANSWER-Ca++ and
Mg++
Name two complement components that are anaphylatoxins - CORRECT ANSWER-
C3a and C5a
What is the minimum number of days a BBK specimen must be kept? - CORRECT
ANSWER-Seven days post transfusion
Name two groups for which weak D testing is required - CORRECT ANSWER-Donors,
NB of D- Moms
What is required for crossmatch specimen to be used longer than three days? -
CORRECT ANSWER-Known history, not pregnant or transfusion last three months
What can be used to neutralize heparin? - CORRECT ANSWER-Protamine sulfate
If given Rh positive cells to Rh negative person, what does standards require? -
CORRECT ANSWER-A policy?(and a Rhig policy)
Name three requirements for when blood must be irrradiated - CORRECT ANSWER-
TA-GVHD risk; blood relative; HLA-matched
Why can't you use an EDTA specimen for Donath Landsteiner test? - CORRECT
ANSWER-It wouldn't lyse C'
What is meant by thermal amplitude? - CORRECT ANSWER-How high temp of reaction
What is ZZAP? - CORRECT ANSWER-Ficin OR papain AND DDT
What concentration of albumin is used as a serum control? - CORRECT ANSWER-6%
What is the source Ficin? - CORRECT ANSWER-Fig
What lectin agglutinates ficin-treated cells? - CORRECT ANSWER-Glycine soja (soy
bean)
What is the specificity of Phaseolus lunatus lectin? - CORRECT ANSWER-A lima bean
All acquired B cells were originally what type? - CORRECT ANSWER-A
Glycine soja also agglutinates what types of polyagg? - CORRECT ANSWER-
T(bacterial, low sialic acid). Tn (mutation)(also A lectins)
