TCA Cycle (MCBM Exam 2) Questions
and Answers 100% Correct
Where does the TCA cycle occur? - ANSWER - mitochondrial matrix
What is the energy production overview of the TCA cycle? - ANSWER - -Stage 1: AcetylCoA
produced from carbohydrates, fats, or proteins
-Stage 2: Generates reducing equivalents (NADH & FADH2) for electron transport
-Stage 3: Reducing equivalents generate a proton gradient used to drive ATP synthesis
____ ____ are the biggest contributor to acetyl CoA production - ANSWER - fatty acids
-but recall brain and RBCs can't use fatty acids for energy (brain bc of blood brain barrier, and
RBCs bc they dont have mitochondria)
What are the 5 cofactors of the pyruvate dehydrogenase? - ANSWER - 1. Thiamine-TPP (Vit
B1)
2. Riboflavin - FAD (Vit B2)
3. Niacin - NAD+ (Vit B3)
4. Pantothenate - Coenzyme A (Vit B5)
5. Lipoate
the PDH complex has 3 enzymes: - ANSWER - E1, E2, E3
E1 - ANSWER - Pyruvate Dehydrogenase
E2 - ANSWER - dihydrolipoyl transacetylase
E3 - ANSWER - dihydrolipoyl dehydrogenase
and Answers 100% Correct
Where does the TCA cycle occur? - ANSWER - mitochondrial matrix
What is the energy production overview of the TCA cycle? - ANSWER - -Stage 1: AcetylCoA
produced from carbohydrates, fats, or proteins
-Stage 2: Generates reducing equivalents (NADH & FADH2) for electron transport
-Stage 3: Reducing equivalents generate a proton gradient used to drive ATP synthesis
____ ____ are the biggest contributor to acetyl CoA production - ANSWER - fatty acids
-but recall brain and RBCs can't use fatty acids for energy (brain bc of blood brain barrier, and
RBCs bc they dont have mitochondria)
What are the 5 cofactors of the pyruvate dehydrogenase? - ANSWER - 1. Thiamine-TPP (Vit
B1)
2. Riboflavin - FAD (Vit B2)
3. Niacin - NAD+ (Vit B3)
4. Pantothenate - Coenzyme A (Vit B5)
5. Lipoate
the PDH complex has 3 enzymes: - ANSWER - E1, E2, E3
E1 - ANSWER - Pyruvate Dehydrogenase
E2 - ANSWER - dihydrolipoyl transacetylase
E3 - ANSWER - dihydrolipoyl dehydrogenase
