ONS CHEMOTHERAPY IMMUNOTHERAPY CERTIFICATE QUESTIONS WITH CORRECT ANSWERS

ONS CHEMOTHERAPY
IMMUNOTHERAPY CERTIFICATE
QUESTIONS WITH CORRECT ANSWERS
Defineaneoadjuvantatherapya-arightaanswer--
Treatmentaisagivenaprioratoasurgeryatoashrinkatheatumor

Defineaadjuvantatherapya-arightaanswer--
Additionalacanceratreatmentagivenaafteratheaprimaryatreatmentatoaloweratheariskathatatheac
ancerareoccur

3asubcategoriesaofaalkylatingaagents:a-arightaanswer--1.aNitrogenamustards
2.aPlatinum-
basedaagentsa(doanotapossessaanaalkylagroupabutastillatermedaalkylatingaagentsaasatheyaw
orkasimilarly)
3.aNitrosoureas

Commonaalkylatingaagents:a-arightaanswer--Cyclophosphamidea(Cytoxan)
Ifosfamidea(Ifex)
Bendamustinea(Treanda)

Commonaplatinum-basedaagents:a-arightaanswer--Cisplatina(Platinol)
Carboplatina(Paraplatin)

Whataisauniqueaaboutanitrosoureasaagents?a-arightaanswer--Ableatoacrossatheablood-
brainabarrier;acanabeaeffectiveainatreatingasomeabrainatumors

Commonanitrosoureasaagents:a-arightaanswer--Carmustinea(BiCNU)
Lomustinea(CeeNu)
Streptozocina(Zanosar)

Hypersensitivityacanaoccurawithalateadosesaof:a-arightaanswer--Carboplatin

Theseaagentsaareatypicallyacategorizedaasahighlyaemetogenic:a-arightaanswer--
1.aAlkylatingaagents
2.aNitrosoureas

Pre-administrationalabsaforaalkylatingaagentsaandanitrosoureas:a-arightaanswer--BUN
Creatinine
CBCaw/adiff

, WhataisatheamedicationaMesnaausedafor?a-arightaanswer--
Bladderaprotectantawithaadministrationaofacyclophosphamideaoraifosfamide

Instructaptsareceivinga________atoaavoidaexposureatoacoldaairaandaconsumingacoldafluidsa
fora3-4adaysafollowingatreatmenta-arightaanswer--Oxaliplatin

Howadoaantimetabolitesafunction?a-arightaanswer--
ByablockingaDNAaandaRNAagrowthabyainterferingawithaenzymesaneededaforanormalacellam
etabolism

Antimetabolitesaworkainathea___aphase.a-arightaanswer--S

Commonasideaeffectsaofaantimetabolites:a-arightaanswer--Myelosuppression
GIatoxicities
Photosensitivity
Hand-footasyndrome

Commonaantimetaboliteadrugs:a-arightaanswer--Azacitidine
Capecitabine
5-FU
Cytarabine
Decitabine
Methotrexate

TheainstituteaforaSafeaMedicationaPracticesarecommendsawhatarouteaofaadministrationafor
avincristine?a-arightaanswer--IVapiggybackaviaagravity



Anthracyclineaantitumoraabxaworkaby:a-arightaanswer--
InterferingawithaenzymesanecessaryaforaDNAatoareplicateainaALLaphasesaofatheacellacycle

Theatwoamajoraclassificationsaofaantitumoraantibioticsaare:a-arightaanswer--Anthracyclines
Non-anthracyclines

Commonaanthracyclineaantitumoraabx:a-arightaanswer--Daunorubicin
Doxorubicin
Epirubicin
Idarubicin

Theaantitumoraabxa___________aisanotaanaanthracycline,abutahasaanthracycline-
typeaproperties.a-arightaanswer--Mitoxantrone

Commonanon-anthracyclineaantitumoraabx:a-arightaanswer--ActinomycinaD
MitomycinaC
Bleomycin

Monitoringanecessaryawithadoxorubicin:a-arightaanswer--Vesicanta-->aextravasation