Pharmacology-Antidepressants Questions and Answers

Pharmacology-Antidepressants
Questions and Answers
Antidepressant therapeutic effects may not be seen for two to four weeks:

a.serotonin-specific reuptake inhibitors (SSRIs)

b. tricyclics antidepressants

c. both

d. neither

✓ ~~~ c. both



Buspirone:

a. is effective in treating depression

b. is cross-tolerant with benzodiazepines

c. does not produce significant levels of sedation

d. is a benzodiazepine

e. has a rapid onset of action.

✓ ~~~ c. does not produce significant levels of sedation



Primary agent used in chronic management of mania in bipolar disorder:

a. sufentanil (Sufenta)

b. lithium

c. valproic acid (Depakene, Depakote)

, d. imipramine (Tofranil)

e. paroxetine (Paxil)

✓ ~~~ b. lithium



Least likely to cause orthostatic hypotension:

a. desipramine (Norpramin)

b. sertraline (Zoloft)

c. doxepin (Sinequan)

d. tranylcypromine (Parnate)

e. amitriptyline (Elavil, Endep)

✓ ~~~ b. sertraline (Zoloft)



Administration of an MAO inhibitor would most likely cause changes in the CNS

concentration of:

a. acetylcholine

b. histamine

c. norepinephrine

✓ ~~~ c. norepinephrine



Primary use of fluoxetine (Prozac):

a. treating obsessive-compulsive disorder

b. management of morbid obesity