Inflammation Process - N5315 Advanced
Pathophysiology Questions and Correct
Answers
What precipitates the inflammatory process?
✓ ~~~ Cellular injury
What are the first 5 steps of the inflammatory process?
✓ ~~~ Mast cell degranulation, activation of the coagulation cascade, activation
of the kinin cascade, release of chemotactic factors, and the activation of the
complement cascade
What is the function of complement?
✓ ~~~ Functions include bacterial lysis, vasodilation and increased vascular
permeability, triggers mast cell degranulation, chemotaxis, and opsonization
What is kinin turned into?
✓ ~~~ Bradykinin
What is bradykinin responsible for?
✓ ~~~ Pain, chemotaxis, and increased vascular permeability and vasodilation
What system does the coagulation cascade have a role in activating?
✓ ~~~ Kinin system
What factor activates kinin?
✓ ~~~ Factor XII (Hageman factor)
What is the function of the coagulation cascade in the inflammatory process?
✓ ~~~ To form fibrin mesh to stop bleeding and to trap microorganisms
What does the plasmin in the coagulation cascade do?
✓ ~~~ Activates complement and kinin system
What do released chemotactic factors attract?
✓ ~~~ Neutrophils, eosinophils and monocytes
How soon do neutrophils show up at the site of injury?
✓ ~~~ 6-8 hours
How soon do monocytes show up at the site of the injury?
✓ ~~~ 1-7 days
What are neutrophils and monocytes responsible for at the site of injury?
✓ ~~~ Phagocytosis
Pathophysiology Questions and Correct
Answers
What precipitates the inflammatory process?
✓ ~~~ Cellular injury
What are the first 5 steps of the inflammatory process?
✓ ~~~ Mast cell degranulation, activation of the coagulation cascade, activation
of the kinin cascade, release of chemotactic factors, and the activation of the
complement cascade
What is the function of complement?
✓ ~~~ Functions include bacterial lysis, vasodilation and increased vascular
permeability, triggers mast cell degranulation, chemotaxis, and opsonization
What is kinin turned into?
✓ ~~~ Bradykinin
What is bradykinin responsible for?
✓ ~~~ Pain, chemotaxis, and increased vascular permeability and vasodilation
What system does the coagulation cascade have a role in activating?
✓ ~~~ Kinin system
What factor activates kinin?
✓ ~~~ Factor XII (Hageman factor)
What is the function of the coagulation cascade in the inflammatory process?
✓ ~~~ To form fibrin mesh to stop bleeding and to trap microorganisms
What does the plasmin in the coagulation cascade do?
✓ ~~~ Activates complement and kinin system
What do released chemotactic factors attract?
✓ ~~~ Neutrophils, eosinophils and monocytes
How soon do neutrophils show up at the site of injury?
✓ ~~~ 6-8 hours
How soon do monocytes show up at the site of the injury?
✓ ~~~ 1-7 days
What are neutrophils and monocytes responsible for at the site of injury?
✓ ~~~ Phagocytosis
