ASCP BLOOD BANK Questions with Correct
Answers
Which reagent is produced by isolating a single clone of B-lymphocytes
secreting antibodies of the same specificity? Correct Answer-
Monoclonal antisera
Which of the following is recommended for specimen collection when
performing a DAT to prevent complement attachment to RBCs
associated with refrigerated, clotted specimens. Correct Answer-EDTA
(purple stopper
The DAT is used to : Correct Answer-detect antibody in vivo
sensitization of RBCs
Which is/are FDA approved monoclonal anti-sera : Correct Answer-
anti-A
anti-D
anti-IgG
A hybrid cell formed by the fusion of a myeloma cell and an antibody-
producing B lymphocyte Correct Answer-Hybridoma
What immunodominant sugar is responsible for group "A" specificity?
Correct Answer-N-acetylgalactosamine
Individuals with hh genotype are known as Correct Answer-Bombay
,Which of the following is a major subgroup of A? Correct Answer-
Dolichos biflorus should give a positive reaction with this RBC type
Correct Answer-A1
Which of the following is NOT a characteristic of ABO antibodies.
Correct Answer-Are primarily IgG and require AHG for detection
Which of the following is/are possible genotypes for an individual who
is group A? Correct Answer-
If a patient has the following genes (A,B & H) what is their ABO blood
group? Correct Answer-AB
Which ABO Blood Group has the most detectable "H" ? Correct
Answer-O
Which of the following can cause a discrepancy between the forward
and reverse ABO type? Correct Answer-age
diseases that cause production of excess proteins
immunodeficiency disorders
, Acquired B occurs Correct Answer-in some group A1 individuals with
exposure to bacterial enzymes as a result of gastrointestinal
disorders/carcinomas.
What is the purpose of washing before the addition of AHG reagent?
Correct Answer-What color dye is FDA approved for addition in the
mfg of polyclonal AHG?
To remove traces of human serum and unbound antibodies to prevent
neutralization of AHG reagent
What color dye is FDA approved for addition in the mfg of polyclonal
AHG? Correct Answer-
Which of the following is NOT considered a benefit to using
monoclonal reagents? Correct Answer-source for transmission of human
diseases
The antiglobulin test is used to detect RBCs sensitized with: Correct
Answer-IgG
The IAT is used to: Correct Answer-screen for patient serum antibodies
A mother is Rh+ and a father is Rh- Their baby is Rh-. It may be
concluded Correct Answer-The father is heterozygous D
Which of the following indicates Rh null Correct Answer----/---
Answers
Which reagent is produced by isolating a single clone of B-lymphocytes
secreting antibodies of the same specificity? Correct Answer-
Monoclonal antisera
Which of the following is recommended for specimen collection when
performing a DAT to prevent complement attachment to RBCs
associated with refrigerated, clotted specimens. Correct Answer-EDTA
(purple stopper
The DAT is used to : Correct Answer-detect antibody in vivo
sensitization of RBCs
Which is/are FDA approved monoclonal anti-sera : Correct Answer-
anti-A
anti-D
anti-IgG
A hybrid cell formed by the fusion of a myeloma cell and an antibody-
producing B lymphocyte Correct Answer-Hybridoma
What immunodominant sugar is responsible for group "A" specificity?
Correct Answer-N-acetylgalactosamine
Individuals with hh genotype are known as Correct Answer-Bombay
,Which of the following is a major subgroup of A? Correct Answer-
Dolichos biflorus should give a positive reaction with this RBC type
Correct Answer-A1
Which of the following is NOT a characteristic of ABO antibodies.
Correct Answer-Are primarily IgG and require AHG for detection
Which of the following is/are possible genotypes for an individual who
is group A? Correct Answer-
If a patient has the following genes (A,B & H) what is their ABO blood
group? Correct Answer-AB
Which ABO Blood Group has the most detectable "H" ? Correct
Answer-O
Which of the following can cause a discrepancy between the forward
and reverse ABO type? Correct Answer-age
diseases that cause production of excess proteins
immunodeficiency disorders
, Acquired B occurs Correct Answer-in some group A1 individuals with
exposure to bacterial enzymes as a result of gastrointestinal
disorders/carcinomas.
What is the purpose of washing before the addition of AHG reagent?
Correct Answer-What color dye is FDA approved for addition in the
mfg of polyclonal AHG?
To remove traces of human serum and unbound antibodies to prevent
neutralization of AHG reagent
What color dye is FDA approved for addition in the mfg of polyclonal
AHG? Correct Answer-
Which of the following is NOT considered a benefit to using
monoclonal reagents? Correct Answer-source for transmission of human
diseases
The antiglobulin test is used to detect RBCs sensitized with: Correct
Answer-IgG
The IAT is used to: Correct Answer-screen for patient serum antibodies
A mother is Rh+ and a father is Rh- Their baby is Rh-. It may be
concluded Correct Answer-The father is heterozygous D
Which of the following indicates Rh null Correct Answer----/---
