Immunology (HMX, etc); Questions & Answers
100% Correct
Neutrophils Answer-A type of white blood cell that engulfs invading microbes and
contributes to inflammation.
Monocytes Answer-A type of white blood cell that transforms into macrophages when
entering tissue and engulfs microbes then undergoes apoptosis. One of the main components
of pus.
dendritic cells Answer-Tissue resident cells involved in innate immunity that get their
name from their resemblance to dendrites. They have innate receptors on their surface and
they release pro-inflammatory cytokines.
Macrophages Answer-What monocytes become, also exist as tissue resident cells. Very
effective at phagocytosis. They also secrete pro-inflammatory cytokines.
mast cells Answer-Tissue resident cells that release inflammatory mediators (such as
histamine) as well as cytokines.
ICAM-1 Answer-endothelial cell surface molecule, binds to LFA-1 to promote stronger
(stable rest) adhesion of leukocytes
E-selectin Answer-endothelial cell surface molecule, binds to E-selectin-ligand to promote
weaker (rolling) adhesion of leukocytes
, Immunology (HMX, etc); Questions & Answers
100% Correct
Plasmacytoid dendritic cells (pDCs) Answer-sentinel cell that detects viruses and releases
type I IFN
Type I interferons (IFNs) Answer-group of cytokines that initiate signaling to activate
antiviral state
Anti-viral state Answer-Virus-infected cells and pDCs produce Type 1 Interferons (IFN-a
and IFN-b)
IFNs alert neighboring uninfected cells prompting the production of anti-viral proteins that
block viral replication when bound to double stranded RNA
Pathogen-associated molecular patterns (PAMPs) Answer-Molecules associated with
groups of pathogens that are not found in vertebrates. Recognized by immune cells to initiate
response
Lipopolysaccharide (LPS) Answer-a PAMP expressed on many gram-negative bacteria
Pattern Recognition Receptors (PRRs) Answer-Found on phagocytes, dendritic cells,
endothelial cells, and lymphocytes
Recognize and bind PAMPs
100% Correct
Neutrophils Answer-A type of white blood cell that engulfs invading microbes and
contributes to inflammation.
Monocytes Answer-A type of white blood cell that transforms into macrophages when
entering tissue and engulfs microbes then undergoes apoptosis. One of the main components
of pus.
dendritic cells Answer-Tissue resident cells involved in innate immunity that get their
name from their resemblance to dendrites. They have innate receptors on their surface and
they release pro-inflammatory cytokines.
Macrophages Answer-What monocytes become, also exist as tissue resident cells. Very
effective at phagocytosis. They also secrete pro-inflammatory cytokines.
mast cells Answer-Tissue resident cells that release inflammatory mediators (such as
histamine) as well as cytokines.
ICAM-1 Answer-endothelial cell surface molecule, binds to LFA-1 to promote stronger
(stable rest) adhesion of leukocytes
E-selectin Answer-endothelial cell surface molecule, binds to E-selectin-ligand to promote
weaker (rolling) adhesion of leukocytes
, Immunology (HMX, etc); Questions & Answers
100% Correct
Plasmacytoid dendritic cells (pDCs) Answer-sentinel cell that detects viruses and releases
type I IFN
Type I interferons (IFNs) Answer-group of cytokines that initiate signaling to activate
antiviral state
Anti-viral state Answer-Virus-infected cells and pDCs produce Type 1 Interferons (IFN-a
and IFN-b)
IFNs alert neighboring uninfected cells prompting the production of anti-viral proteins that
block viral replication when bound to double stranded RNA
Pathogen-associated molecular patterns (PAMPs) Answer-Molecules associated with
groups of pathogens that are not found in vertebrates. Recognized by immune cells to initiate
response
Lipopolysaccharide (LPS) Answer-a PAMP expressed on many gram-negative bacteria
Pattern Recognition Receptors (PRRs) Answer-Found on phagocytes, dendritic cells,
endothelial cells, and lymphocytes
Recognize and bind PAMPs
