how many ways can proton pumps be activated?
3
H2RAs block ___ pathways of proton pump activation
1
___ are the most potent because they block the pump itself
PPIs
___ only bind H+ that is pumped out of parietal cell by proton pump
antacids
what is the newest non-pharm recommendation added to the guidelines?
avoid tobacco
IV or PO: stress ulcer prophylaxis
IV
IV or PO: control of GI bleeding
IV
IV or PO: management of severe erosive esophagitis
IV
IV, PPI, or Stop: criteria for prophylaxis no longer met
stop PPI
IV or PPI: GI ulceration
, PO
IV or PPI: erosive esophagitis
PO
IV, PPI, or Stop: event resulting in initiation controlled
PO or stop
there is a drug interaction between ___ and P2Y12 inhibitors like
clopidogrel
PPIs
true or false: H2RAs are a good choice in elderly patients
false
1st line in pregnancy for GERD
antacids
what antacids should be avoided when treating GERD in pregnancy
sodium bicarb and mg trisilicate
2nd line in pregnancy for GERD
sucralfate
3rd line in pregnancy for GERD
H2RA
Safest H2RA for pregnant women