Concepts
Absorption and factors that affect it - correct answer-Movement from administration site to
various tissues
factors: solubility, good circulatory flow
additive effect - correct answer-A + B = AB
have similar mechanisms, so the effects of two drugs taken separately EQUALS effects of
drugs taken together
adverse drug reactions - correct answer-unintended reactions that occurs when a medication
is given at the appropriate dose
can be:
Non-therapeutic, unintended, predictable/unpredictable, varies in severity
agonists - correct answer-drugs that bind with a receptor and increases the response
antagonist effects - correct answer-AB less than A + B
taking the drugs together have a less effect than taking them separately
antagonists - correct answer-drug that bind with receptor and blocks or inhibits a response
Bioavailability - correct answer-Amount of drug leftover after its been metabolized
Biotransformation - correct answer-structure of drug is chemically altered after metabolism
brand name drug - correct answer--a drug's commercial name, that is capitalized
-one generic drug can have multiple brand names
examples: Tylenol --> acetaminophen; Advil --> ibuprofen
competitive antagonists - correct answer-competes with an agonist for a receptor site
if given in large doses it will decrease the response of an agonist
contraindictions - correct answer-potential to cause a serious or life-threatening adverse
drug reaction in relation to a factors like food, combinations with other meds and certain
populations
cumulative effect - correct answer-occurs when the body is unable to excrete an existing
dose of medication for another dose is administered
-can be caused by a metabolic change in the body such as in liver or kidney