BMSC 220 final || with 100% Error-free Answers.

Outer membrane of mitochondria correct answers - contains porins= permeable to all molecules below 10 kDa - similar chemical composition to plasma membrane Inner membrane of mitochondria correct answers - primary site of ATP production - contains cardiolipin -80% protein - has cristae cardiolipin correct answers - makes the inner membrane impermeable to proteins - special phospholipid with 4 fatty acid chains # of cristae correct answers - varies with the energy needs of the cell - increases with increasing energy needs Inter-membrane space correct answers -similar composition to cytoplasm (due to porins) Matrix correct answers - 50% protein - contains most enzymes involved in oxidative metabolism - Higher pH and has a negative charge relative to cytoplasm - site of mito DNA, RNA and protein synthesis Mitochondrial genome correct answers - located in matrix - circular w/ 1 origin of replication - maternally inherited What does the mitochondrial genome encode for? correct answers - rRNAs for mitochondrial ribosomes - 22 mitochondrial tRNAs - 12 proteins in the ETC where does the majority of proteins needed in the mitochondria encoded? correct answers - nuclear DNA Why are there separate tRNAs in the mitochondria? correct answers - Mito uses a different genetic code (different codon- A.A translation) Why is only 22 tRNA suffiecient for mitochondria? correct answers - Uracil tRNAs have extreme wobble allows fewer tRNAs to be needed