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Samenvatting medische technieken

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(Behaalde score:19/20) Deze samenvatting bevat alle info uit de acco cursus gecombineerd met extra info en foto's uit de slides.

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Uploaded on
June 1, 2024
Number of pages
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Written in
2023/2024
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Hoofdstuk: Medische technieken i.v.m bevruchting en
implantatie

1. In vitro-fertilisatie (ivf) = reageerbuisbevruchting =
proefbuisbevruchting


 Eicellen worden net voor ovulatie geaspireerd uit ovarium
 induceren van superovulatie
 door toediening gonadotrope hormonen komen een aantal follikels tot rijping


 Eicel wordt in vitro bevrucht met sperma van partner of donor
 zygote laat men ontwikkelen tot vroege morulastadium en vervolgens wordt ze in uterus
moeder gebracht
 meestal worden 5-tal bevruchte eicellen ingeplant omdat gemiddeld slecht 1/5 eicellen
zich implanteert


 Eerste ‘proefbuisbaby’ = Louise Brown




Variant van ivf methode:
1) Eicel en sperma in ampulla eileider brengen en dan verdere natuurlijke ontwikkeling zijn
gang laten gaan
2) Zygote die in vitro ontstaan is onmiddellijk in eileider plaatsen


 Beiden niet steeds toepasbaar door deficiënt transport van eicel in eileider of
ondoorgankelijkheid van eileider




2. Intracytoplasmatische sperma-injectie of ICSI

 1 zaadcel wordt rechtstreeks in 1 eicel geïnjecteerd
 De bevruchting gebeurt dus kunstmatig
 Eicellen worden na pick-up uit eierstokken onder microscoop bekeken en ontdaan van
cumuluscellen  deels manueel met micropipet, deels enzymatisch

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