Lesson 1: Introduction to proteins (in relation to teeth)
Proteins in teeth mineralisation
- Enamel = Amelogenins and enamelling thought to form the framework for
mineralization
- Dentin = Collagen, glycoproteins, proteoglycans
- Cementum = Collagen and glycoproteins
- Proteins have a mechanical, structural and transportational function in the body.
- Crucial role as enzymes (biological catalysts)
- Shape of the protein determines structure and function. Determined by the
information in the DNA sequence of the gene.
- Amino acids line up linearly into chains. They have polar and non polar side chains
determining the charge. The hydrophobic region contains the non polar side chains.
The hydrogen bonds form the polar side chains on the outside of the molecule.
Amino acids
- 20 amino acids common to all living things
- Amino acids are water soluble and electrically charged at physiological ph (ph 7)
- Differs by the R group
- Asymmetric carbon atoms - enantiomers or optical isomers
Proteins in teeth mineralisation
- Enamel = Amelogenins and enamelling thought to form the framework for
mineralization
- Dentin = Collagen, glycoproteins, proteoglycans
- Cementum = Collagen and glycoproteins
- Proteins have a mechanical, structural and transportational function in the body.
- Crucial role as enzymes (biological catalysts)
- Shape of the protein determines structure and function. Determined by the
information in the DNA sequence of the gene.
- Amino acids line up linearly into chains. They have polar and non polar side chains
determining the charge. The hydrophobic region contains the non polar side chains.
The hydrogen bonds form the polar side chains on the outside of the molecule.
Amino acids
- 20 amino acids common to all living things
- Amino acids are water soluble and electrically charged at physiological ph (ph 7)
- Differs by the R group
- Asymmetric carbon atoms - enantiomers or optical isomers
