Nur 239 exam #2 Question with Complete Solutions

Penicillin G *** Correct Answer-- First PCN given PO and IM - PO only about 1/3 of dose is absorbed - IM and IV are most effective (to get therapeutic serum level) (IM is painful) - primarily bactericidal Penicillin V *** Correct Answer-- next type produced - 2/3 absorbed by GI tract, less patent than PCN G - It is effective against mild - moderate infections, including anthrax PCNS (structure) Correct Answer-- beta-lactam antibiotics. - beta-lactam structure interferes with bacterial cell wall synthesis by inhibiting the bacterial enzyme that is necessary for cellular synthesis. - A natural antibacterial agent obtained from mold genus Penicillium. - can be both bacteriostatic and bactericidal depending on the drug and dosage. Amoxicillin (Amoxil) *** Correct Answer-- broad spectrum PCN (aminopenicillins) - Used to treat both Gram +/- bacteria. - Not all that broad after all.