Chemotherapy Drugs Final Questions 2024/2025 100% Solved | Top graded A+

Cancer cells are characterized by - persistent proliferation, invasive growth, and the ability to form metastases. Cancer can be treated with three basic modalities: - surgery, radiation therapy, and drug therapy Agents used for drug therapy fall into two main groups: - (1) cytotoxic agents and (2) noncytotoxic agents, such as hormones, immunomodulators, and targeted drugs. Surgery and/or irradiation are the treatments of choice for - most solid tumors. Drugs are the treatment of choice for disseminated cancers which are: - leukemias, disseminated lymphomas, widespread metastases Drugs are also used as adjuvants to surgery and irradiation to kill - malignant cells that surgery and irradiation leave behind The cell cycle has four major phases: - G1, in which cells prepare to synthesize deoxyribonucleic acid (DNA); S, in which cells synthesize DNA; G2, in which cells prepare for mitosis (division); and M, in which cells actually divide. Following mitosis, the resulting daughter cells may either enter G1 and repeat the cycle, or enter G0 and become mitotically dormant. The growth fraction of a tissue is defined as the ratio of - proliferating cells to cells in G0. Tissues with a large percentage of proliferating cells and few cells in G0 have a - high growth fraction. Tissues composed mostly of G0 cells have a - low growth fraction