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Chemistry in everyday life

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  • May 10, 2024
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Chapter—> Chemistry in Everyday Life

Medicines or Drugs

Chemicals which may be used for the treatment of diseases and for reducing the suffering from
pain are called medicines or drugs.

The branch of science which makes use of chemicals for the treatment of disseases [therapeutic
effect] is called chemotherapy.
Some important classes of drugs are

Antacid

The chemical substances which neutralize the excess acid in gastric juice and raise the pH to an
appropriate level in stomach are raUed antacids.

The most commonly used antacids are weak bases such as sodium bicarbonate [sodium
hydrogencarbonate, NaHCO3), magnesium hydroxide [Mg(OH)2] and aluminium hydroxide
[Al(OH)3].

Generally liquid antacids are more effective than tablets because .. have more surface area
available for interaction and neutralisation acid.

Milk is a weak antacid.

Histamine stimulates the secretion of pepsin and hydrochloric acid. The drug cimetidine
[Tegamet] was designed to prevent the interaction of histamine with the receptors present in the
stomach Cimetidine binds to the receptors tbat triggers the release of acid the stomach. This
results in release of lesser amount of acid. Now ranitidine (zantac), omeprazole and
lansoprazole are used hyperacidity.

Tranquilizers (Psychotherapeutic Drugs)

Chemical substances used for the treatment of stress, anxiety, irritability and mild or even
severe mental diseases, are known as tranquilizers. These affect the central nervous system and
induce sleep for the patients as well as eliminate the symptoms of emotional distress. They are
the common constituents of sleeping pills.

Noradrenaline is one of the neurotransmitter that plays a role in mood change. If the level
of noradrenaline is low, the signal sending activity becomes low, and the person suffers from
depression. In such situations antidepressant drugs are required. These drugs inhibit the
enzymes which catalyse the degradation of noradrenaline. If the enzyme is inhibited, this
important neurotransmitter is slowly metabolized and can activate its receptor for longer

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periods of time, thus counteracting the effect of depression. Iproniazid and phenelzine are two
such drugs.

Barbituric acid and its derivatives viz. veronal, amytal, nembutal, luminal, seconal are
known as barbiturates. Barbiturates are hypnotic, i.e., sleep producing agents.




Equanil is used to control depression and hypertension.

Non-hypnotic chlorodiazepoxide and meprobamate are relatively mild tranquilizers suitable for
relieving tension.

Analgesics

Medicines used for getting relief from pain are called analgesics. These are of two types :

1. Narcotics

Drugs which produce sleep and unconsciousness are called narcotics. Mhese are habit forming
drugs. For example, morphine and codeine. Morphine diacetate is commonly known as heroin.

2. Non-narcotics

These are non-habit forming chemicals which reduce mild to moderate llatn such as headache,
toothache, muscle and joint pain, etc. These are also termed as non-addicti,ve. These drugs do
not produce sleep unconsciousness. Aspirin (2-acetoxybenzoic acid) is most commonly used
analgesic with antipyretic properties. Now these days because its anti-blood clotting action,
aspirin is widely used to
heart-attacks.




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