Lupus NCLEX questions with answers

The nurse is preparing a presentation on systemic lupus erythematosus (SLE). Which statement should the nurse include? (Select all that apply.) A. The etiology is known to be linked to environmental factors. B. Manifestations can be mild to fatal, with remissions and exacerbations. C. The immune complex deposits trigger an inflammatory response. D. SLE is a result of deposition of antigen-antibody complexes in connective tissues. E. The inflammatory response leads to anaphylactic shock. B. Manifestations can be mild to fatal, with remissions and exacerbations. C. The immune complex deposits trigger an inflammatory response. D. SLE is a result of deposition of antigen-antibody complexes in connective tissues. The pathophysiology of systemic lupus erythematosus is a result of the formation of antigen-antibody immunocomplexes that are deposited in the connective tissue and trigger an inflammatory response. The manifestations of the disease can be mild to fatal, and remissions are followed by exacerbations. The inflammatory response leads to tissue damage but not anaphylactic shock (allergic reaction). Although the exact etiology of SLE is unknown, genetic, ethnic, environmental, and hormonal factors play a role in its development. The nurse is assessing a client with systemic lupus erythematosus (SLE). Which clinical manifestation should the nurse expect to observe? (Select all that apply.) A. Red butterfly rash on the face B. Alopecia C. Psoriatic lesions D. Painful or swollen joints E. Leg and eye edema A. Red butterfly rash on the face B. Alopecia D. Painful or swollen joints E. Leg and eye edema Rationale: Painful swollen joints, alopecia, red butterfly rash on the face, and leg and eye edema are all characteristics of SLE. Psoriatic lesions are caused by psoriasis, which is an autoimmune disease characterized by patches of abnormal skin.