440- Final Exam Questions and Complete Solutions

440- Final Exam Questions and Complete Solutions What are the contraindications to transplant? (Select all that apply) Allergies Active malignancy Active infection Active substance abuse Severe cardio/pulmonary/vascular disease - Correct Ans: Active malignancy Active infection Active substance abuse Severe cardio/pulmonary/vascular disease (all but a- allergies) Your patient is recovering from a kidney transplant, you become concerned that there may be a thrombosis in the anastomosis when your patient starts exhibiting: Oliguria, reduced creatinine, and hematuria Polyuria, reduced creatinine, and hematuria Polyuria, elevated creatinine, and hematuria Oliguria, elevated creatinine, and hematuria - Correct Ans: d. Oliguria, elevated creatinine, and hematuria Your liver transplant patient with diabetes is placed on Prednisone. You educate your patient that this medication may cause Hyperglycemia Hypernatremia Hypoglycemia Hyponatremia - Correct Ans: a. Hyperglycemia Association between HLA antigens and diseases is most commonly found in what disease conditions? Autoimmune disorders Malignancies Neurologic diseases Infectious diseases - Correct Ans: a. Autoimmune disorders Any substance that causes your immune system to produce antibodies against it is considered (a/an): Antibody T-Cell B-Cell Antigen - Correct Ans: a. antigen End stage liver failure is often caused by (select all that apply) Alcoholic Cirrhosis Hepatitis C Hepatocellular Cancer Uncontrolled Diabetes Nonalcoholic Steatohepatitis - Correct Ans: Alcoholic Cirrhosis Hepatitis C Hepatocellular Cancer Nonalcoholic Steatohepatitis (all but Uncontrolled Diabetes) One function of cell-mediated immunity is Formation of antibodies Opsonization of antigens to allow phagocytosis by neutrophils Activation of the complement system Surveillance for malignant cell changes - Correct Ans: d. Surveillance for malignant cell changes Which of the following accurately describes rejection following transplantation? Hyperacute reaction can usually be avoided if crossmatching is done prior totransplantation Chronic rejection can be treated with tacrolimus or cyclosporine Hyperacute rejection can be treated with OKT3 Acute rejection can be treated with sirolimus or tacrolimus - Correct Ans: a. Hyperacute reaction can usually be avoided if crossmatching is done prior totransplantation Your patient is experiencing an antibody mediated rejection you explain to her that her treatment option includes: Cyclosporine Plasmapheresis