SCNM Q3 Microbiology Final ExamWith Verified Solution 2024

Bordetella Pertussis (Whooping cough) - ansGram - Coccobacilli -Acute Respiratory, Severe coughing episodes (Bronchial pneumonia, acute encephalopothy -killed 5-10,000/yr before vaccine (available 2013/2014) -S&S: runny nose, sneezing, mild cough, low-grade fever, pneumonia, whoop sound inhaling, cyanosis, vomiting -Petrussis toxin a-b subunit - attaches/blocks cilia movement, increases cAMP levels (mucous secretions) -Filamentous hemagglutinin - attaches to human cilia -Transmission - person-person - can only colonize ciliated epithelial cells of respiratory mucosa -common childhood before vaccine; incubation 1-2wks, most infectious early but reamins infectious for 5 wks Chlamydia Trachomatis (G- indeterminate cocci) - ansConjunctivitis (Trachoma) - most common preventable cause of blindness in world, spread by touching eye, nose, or vaginal secretions (direct contact, towels/fomites, or eye seeking flies Genital Infection - (common STD) - 1/2m, 3/4w asymptomatic -Women - pelvic inflammatory disease - inf of uterus, fallopian tube/ovary, infertility, vaginal discharge (milky white/yellow) ****Painful urination** -Men - epididymitis - inflammed colled tube on testis, urethritis, penis discharge (white), ***Painful urination**, 5x more likely to become infected with HIVShigella Dysenteriae (Shigellosis) - ansG- Rod (Lactose Fermentation - ) Fecal-oral transmission -S&S - abdominal pain, bloody, mucoid diarrhea, abdominal tenderness, fever, vomiting, dehydration -Endemic in poor sanitation areas -Incubation 24-48hrs (Mild - watery diarrhea; severe - dysentery/abd pain/fever; Lasts 7 days) **Similar to enteroinvasive E.Coli (EIEC) -Toxin - inhibits cellular protein synthesis, leads to flulid accumulation due to poor absorption = shigella toxin (A-B toxin: A=active portion, B=binding por