Laboratory Evaluation: Cytochemical Stains and Bone Marrow 2024/2025

Laboratory Evaluation: Cytochemical Stains and Bone MarrowLAP Score: 1+ score - correct answer Slight LAP activity LAP score: 2+ and 3+ score - correct answer Moderate LAP activity LAP score: 4+ score - correct answer Marked LAP activity LAP scoring - correct answer Grading categories = 0, 1+, 2+, 3+, and 4+ Number of cells in each category = Total = 100 Multiply # of cells counted by grade and then add up all category values Example: 0 x 60 = 0 1 x 20 = 20 2 x 14 = 28 3 x 5 = 15 4 x 1 = 4 Total score = 0+20+28+15+4 = 67 Interpretation of score: Reference range = 20-100 Low score 20 = consistent with Chronic Myelogenous Leukemia (CML) High score 100 = consistent with Leukemoid Reaction ****LAP is inhibited by EDTA, so specimen is collected in a heparinized capillary or blood tube****