PEBC EE Q&As (Correct 100%)

Thiazide Diuretics AEs 'MICH' -Metolazone -Indapamide -Chlorthalidone (thiazide-like) -HCTZ correct answers -Impotence -Hypokalemia (inc DIGOXIN toxicity) -Inc Urate (CI in Gout) -Inc BG (CI in DM, lowers antihyperglycemic effect of drugs) -Inc Lipids -Hypotension (effect lowered by NSAIDs) *not effective in renal dysfunction Regulators of Body Temperature correct answers -urine -skin -sweat glands Teratogenic Drugs cause damage during? correct answers 2nd- 8th week Components in saliva? correct answers Lysozyme, IgA, Amylase Factors responsible for transfer of drug across placental barrier correct answers Conc of drug Molecular size of drug Drug solubility Derived from Tryptophan? correct answers Niacin, Melatonin, ~5-HTP~5-HT (serotonin) Tx thrombocytopenia correct answers Oprelvekin (IL-11) Iron correct answers -most abundant metal in the body -excess: hemochromatosis -antidote OD: deferoxamine Epinephrine derived from? correct answers Phenylalanine->Tyrosine->Dopa->Dopamine->NE->EPI Aminoglycoside SEs: 'AMINO' correct answers Allergy M neuroMuscular blockade Inactivated when physically mixed with B-lactams Nephrotoxicity Ototoxicity, Optic nerve toxicity